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Greengard, P.
Greengard, Paul,
Paul Greengard (American neuroscientist)
Paul Greengard (Amerikaans biochemicus)
Paul Greengard (neurobiolog amerykański)
Paul Greengard (neuroscienziato statunitense)
Paul Greengard (US-amerikanischer Biochemiker, Nobelpreisträger für Medizin)
Грингард, Пол
Пол Грингард
Пол Грінгард
Пол Грынгард
פול גרינגרד
بول غرينغارد
پائول گرینگارد
پال گرینگارڈ
پاول گرین گارڈ
Creation class: 
Language material
Creation role: 
Related names: 
American College of Neuropsychopharmacology
Brooker, Gary
Costa, Erminio
Drummond, George I.
Dumont, Jacques E. (1931-)
Johns Hopkins University
Nestler, Eric J. (1954-)
Nestler, Eric Jonathan (1954-)
Paoletti, R.
Paoletti, Rodolfo
Paoletti, Rodolfo (1931- ))
Robison, G. Alan (1934-...)
Yale University Affiliation (see also from)
127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein., A
20-Hydroxyeicosa-tetraenoic acid (20 HETE) activates protein kinase C. Role in regulation of rat renal Na+,K+-ATPase.
38,000-dalton membrane protein (p38) present in synaptic vesicles., A
87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization., The
Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons.
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis.
actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines., The
Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein phosphatase from toad bladder.
Activation/deactivation of renal Na+,K(+)-ATPase: a final common pathway for regulation of natriuresis.
Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projetion neurons via different mechanisms
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.
Activation of NMDA receptors induces rapid dephosphorylation of the cytoskeletal protein MAP2.
Activation of the cAMP/PKA/DARPP-32 Signaling Pathway is Required for Morphine Psychomotor Stimulation but not for Morphine Reward
Active catalytic fragment of Ca2+/calmodulin-dependent protein kinase II. Purification, characterization, and structural analysis.
Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral agents.
Adenosine 3',5'-monophosphate content in rat caudate nucleus: demonstration of dopaminergic and adrenergic receptors.
Adenosine 3',5-monophosphate-dependent phosphorylation of a specific protein in synaptic membrane fractions from rat cerebrum.
Adenosine 3',5'-monophosphate-dependent protein kinase from brain.
adenosine 3',5'-monophosphate-dependent protein kinase from Escherichia coli., An
Adenosine 3',5'-monophosphate: electrophysiological evidence for a role in synaptic transmission.
Adenosine 3',5'-monophosphate in nervous tissue: increase associated with synaptic transmission.
Adenosine 3':5'-monophosphate receptor proteins in mammalian brain.
Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin
Advances in biochemical psychopharmacology.
Advances in cyclic nucleotide research.
Advances in second messenger and phosphoprotein research. Vol. 23
After-potentials in mammalian non-myelinated nerve fibres.
Aldosterone-induced increase in protein phosphatase activity of toad bladder.
Aldosterone synthesis by adrenal mitochondria. 3. Participation of cytochrome P-450.
Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines
alpha and gamma 1 isoforms of protein phosphatase 1 are highly and specifically concentrated in dendritic spines, The
Alterations in 5-HT1B Receptor Function by p11 in Depression-Like States
Altered processing of Alzheimer amyloid precursor protein in response to neuronal degeneration.
Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E.
Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement., The
Alzheimer amyloid protein precursor is localized in nerve terminal preparations to Rab5-containing vesicular organelles distinct from those implicated in the synaptic vesicle pathway
Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment.
Alzheimer beta/A4 amyloid precursor protein in human brain: aging-associated increases in holoprotein and in a proteolytic fragment.
Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I.
Amplification of dopaminergic signaling by a positive feedback loop
Amyloid- beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay
Amyloid beta peptide formation in cell-free preparations: Regulation by protein kinase C calmodulin, and calcineurin
amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo., The
Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities.
analysis of postmortem brain samples from 32 alcoholic and nonalcoholic individuals for protein III, a neuronal phosphoprotein., An
analysis of synapsin II, a neuronal phosphoprotein, in postmortem brain tissue from alcoholic and neuropsychiatrically ill adults and medically ill children and young adults., An
Anatomy of cerebellar Purkinje cells in the rat determined by a specific immunohistochemical marker.
- and delta -opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons
Anti-synapsin monoclonal antibodies: epitope mapping and inhibitory effects on phosphorylation and Grb2 binding
Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein.
Antibodies to synaptophysin interfere with transmitter secretion at neuromuscular synapses.
Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex.
Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications.
APP localization and trafficking in the central nervous system
Application of a translational profiling approach for the comparative analysis of CNS cell types.
Arctic Alzheimer mutation favors intracellular amyloid-[beta] production by making amyloid precursor protein less available to [alpha]-secretase, The
Arctic mutation favors intracellular amyloid-β production
Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.
ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins
ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Molecular cloning and nucleotide sequence.
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr
ARPP-39, a membrane-associated substrate for cyclic AMP-dependent protein kinase present in neostriatal neurons.
assay method for cyclic AMP and cyclic GMP based upon their abilities to activate cyclic AMP-dependent and cyclic GMP-dependent protein kinases., An
Assay of cyclic GMP by activation of cyclic GMP-dependent protein kinase.
Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals.
Autophosphorylation of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain.
Autophosphorylation reversibly regulates the Ca2+/calmodulin-dependence of Ca2+/calmodulin-dependent protein kinase II.
Autoregulation of phosphorylation of the nicotinic acetylcholine receptor.
B''/PR72 subunit mediates Ca super(2+)-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A, The
B''/PR72 subunit mediates Ca²⁺-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A., The
Backbone 1H, 15N, and 13C resonance assignments of ARPP-19.
Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1.
Bacterial lipopolysaccharide regulates the phosphorylation of the 68K protein kinase C substrate in macrophages.
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses
Beyond the Dopamine Receptor: the DARPP-32/Protein Phosphatase-1 Cascade
Bidirectional changes in synapsin I phosphorylation at MAP kinase-dependent sites by acute neuronal excitation in vivo.
Bidirectional control of phospholipase A2 activity by Ca2+/calmodulin-dependent protein kinase II, cAMP-dependent protein kinase, and casein kinase II.
Bidirectional regulation of DARPP-32 phosphorylation by dopamine
Bidirectional regulation of Na+,K(+)-ATPase activity by dopamine and an alpha-adrenergic agonist.
Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation.
Biochemical and immunocytochemical characterization of p38, an integral membrane glycoprotein of small synaptic vesicles.
Biochemical characterization of histamine-sensitive adenylate cyclase in mammalian brain.
Biochemical characterization of the dopamine receptor in the mammalian caudate nucleus.
Brain histamine receptors as targets for antidepressant drugs.
Ca2+ and cyclic AMP regulate phosphorylation of same two membrane-associated proteins specific to nerve tissue.
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.
Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.
Ca2+-dependent protein phosphorylation system in membranes from various tissues, and its activation by "calcium-dependent regulator".
[Ca2+]i determines the effects of protein kinases A and C on activity of rat renal Na+,K+-ATPase.
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells.
Calcitonin gene-related peptide potentiates synaptic responses at developing neuromuscular junction.
Calcitonin gene-related peptide regulates phosphorylation of the nicotinic acetylcholine receptor in rat myotubes.
Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes
Calcium/calmodulin-dependent protein phosphorylation in the nervous system of Aplysia.
Calcium-dependent protein phosphorylation during secretion by exocytosis in the mast cell.
Calcium-dependent serine phosphorylation of synaptophysin.
Calcium-dependent transmitter secretion reconstituted in Xenopus oocytes: Requirement for synaptophysin.
Calcium/diacylglycerol-dependent protein kinase and its major 87-kilodalton protein substrate are differentially distributed in rat basal ganglia.
Calcium/phosphatidylserine/diacylglycerol-dependent protein phosphorylation in the Aplysia nervous system.
Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase.
Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes.
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.
Calmodulin-dependent protein kinase and associated substrates in Torpedo electric organ.
Calmodulin-dependent protein kinase from avian erythrocytes.
cAMP-dependent protein kinase phosphorylates the nicotinic acetylcholine receptor.
cAMP-stimulated cation cotransport in avian erythrocytes: inhibition by "loop" diuretics.
Cannabinoid Action Depends on Phosphorylation of Dopamine- and cAMP-Regulated Phosphoprotein of 32 kDa at the Protein Kinase A Site in Striatal Projection Neurons
Cdk5 is essential for adult hippocampal neurogenesis
cDNA and derived amino acid sequences for rat and human synaptophysin., The
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase
Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines
Cellular and subcellular localization of protein I in the peripheral nervous system.
cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones.
cGMP-dependent protein kinase in dorsal root ganglion: Relationship with nitric oxide synthase and nociceptive neurons
Chaperones increase association of tau protein with microtubules
Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.
Characterization of a dopamine-sensitive adenylate cyclase in the rat caudate nucleus.
Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine.
Characterization of rat ARPP-21 mRNA: sequence analysis, tissue distribution, and regulation.
Characterization of synapsin I binding to small synaptic vesicles.
Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2.
Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins.
Characterization of the Neuronal Targeting Protein Spinophilin and Its Interactions with Protein Phosphatase-1
Characterization of tissue-specific transcription by the human synapsin I gene promoter.
Characterization of Transcripts from the Synapsin III Gene Locus
Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes.
Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta /A4 amyloid precursor protein.
Cholecystokinin induces a decrease in Ca2+ current in snail neurons that appears to be mediated by protein kinase C.
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta /A4 amyloid protein precursor.
Cholinergic regulation of protein III phosphorylation in bovine adrenal chromaffin cells.
Chronic treatment of rats with SCH-23390 or raclopride does not affect the concentrations of DARPP-32 or its mRNA in dopamine-innervated brain regions.
CK2 negatively regulates Galphas signaling.
Cloning of cDNA for DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein.
Cloning of cDNAs encoding human synapsins IIa and IIb.
Co-localization of the D1 dopamine receptor in a subset of DARPP-32-containing neurons in rat caudate-putamen.
Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5
Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity
Cocaine Self-Administration in Mice Is Inversely Related to Phosphorylation at Thr34 (Protein Kinase A Site) and Ser130 (Kinase CK1 Site) of DARPP-32
Colocalization of synapsin and actin during synaptic vesicle recycling.
Comparison of gene expression of the dopamine D-2 receptor and DARPP-32 in rat brain, pituitary and adrenal gland.
Comparison of the immunocytochemical localization of DARPP-32 and I-1 in the amygdala and hippocampus of the rhesus monkey.
Computer modeling of synapsin I binding to synaptic vesicles and F-actin: implications for regulation of neurotransmitter release.
Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex.
Correlated light and electron microscopic study of dopaminergic neurons and their synaptic junctions with DARPP-32-containing cells in three-dimensional reaggregate tissue culture.
Correlation Between Elevated Levels of Amyloid beta -Peptide in the Brain and Cognitive Decline
Coupling calcium to SNARE-mediated synaptic vesicle fusion.
Critical Involvement of cAMP/DARPP-32 and Extracellular Signal-Regulated Protein Kinase Signaling in L-DOPA-Induced Dyskinesia
Current methodology
Cyclic 3',5'-nucleotide phosphodiesterase: cytochemical localization in cerebral cortex.
Cyclic AMP-dependent and cyclic GMP-dependent protein kinases of nervous tissue.
Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.
Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium.
Cyclic GMP-specific, high affinity, noncatalytic binding sites on light-activated phosphodiesterase.
cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins., The
Cyclic nucleotide-dependent protein kinases. 3. Purification and properties of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain.
Cyclic nucleotide-dependent protein kinases. 8. An assay method for the measurement of adenosine 3',5'-monophosphate in various tissues and a study of agents influencing its level in adipose cells.
Cyclic nucleotide-dependent protein kinases and some major substrates in the rat cerebellum after neonatal X-irradiation.
Cyclic nucleotides, phosphorylated proteins, and the nervous system.
Cyclic nucleotides, protein phosphorylation, and neuronal function.
Cyclic nucleotides, protein phosphorylation and synaptic function.
Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation
Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum
cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells., The
D-1 and D-2 dopaminergic receptors regulate protein phosphorylation in the rat neurohypophysis.
D sub(1) Dopamine Receptor Activation Reduces GABA sub(A) Receptor Currents in Neostriatal Neurons Through a PKA/DARPP-32/PP1 Signaling Cascade
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution.
DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.
DARPP-32, a dopamine- and cyclic AMP-regulated phosphoprotein in tanycytes of the mediobasal hypothalamus: distribution and relation to dopamine and luteinizing hormone-releasing hormone neurons and other glial elements.
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.
DARPP-32, a phosphoprotein enriched in dopaminoceptive neurons bearing dopamine D1 receptors: distribution in the cerebral cortex of the newborn and adult rhesus monkey.
DARPP-32: an integrator of neurotransmission.
DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.
DARPP-32 development in the caudate nucleus is independent of afferent input from the substantia nigra.
DARPP-32 in the ciliary epithelium of the eye: a neurotransmitter-regulated phosphoprotein of brain localizes to secretory cells.
DARPP-32 Involvement in the Photic Pathway of the Circadian System
DARPP-32 knockout mice exhibit impaired reversal learning in a discriminated operant task.
DARPP-32 mediates serotonergic neurotransmission in the forebrain
DARPP-32 mediates the actions of multiple drugs of abuse.
DARPP-32/protein phosphatase-1 cascade: a model for signal integration., The
DARPP-32: regulator of the efficacy of dopaminergic neurotransmission.
Decrease in Phorbol Ester-Induced Potentiation of Noradrenaline Release in Synapsin I-Deficient Mice
Dephosphorylated synapsin I anchors synaptic vesicles to actin cytoskeleton: An analysis by videomicroscopy
Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons.
Depolarization-induced phosphorylation of specific proteins, mediated by calcium ion influx, in rat brain synaptosomes.
Depolarizing agents and cyclic nucleotides regulate the phosphorylation of specific neuronal proteins in rat cerebral cortex slices.
Determination of intermediary metabolites by enzymic fluorimetry.
Determination of relative levels of cyclic AMP in tissues or cells prelabeled with radioactive adenine.
Development of a dopamine- and cyclic adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation.
Developmental regulation of phosphoprotein gene expression in the caudate-putamen of rat: an in situ hybridization study.
Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity
Different Presynaptic Roles of Synapsins at Excitatory and Inhibitory Synapses
Differential expression of ARPP-16 and ARPP-19, two highly related cAMP-regulated phosphoproteins, one of which is specifically associated with dopamine-innervated brain regions.
Differential expression of protein phosphatase 1 isoforms in mammalian brain
Differential expression of synapsins I and II among rat retinal synapses.
Differential phosphorylation of multiple sites in purified protein I by cyclic AMP-dependent and calcium-dependent protein kinases.
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons.
Discovery of Protein Phosphatase 2C Inhibitors by Virtual Screening
Dissociation and concomitant activation of adenosine 3',5'-monophosphate-dependent protein kinase by histone.
Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition.
Distinct pools of synaptic vesicles in neurotransmitter release
Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity
Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.
Distinct roles of synapsin I and synapsin II during neuronal development.
Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors
Distinguishing among protein kinases by substrate specificities.
Distribution and cellular localization of DARPP-32 mRNA in rat brain.
Distribution of DARPP-32 in the basal ganglia: an electron microscopic study.
Distribution of protein I and regulation of its state of phosphorylation in the rabbit superior cervical ganglion.
Distribution of protein I in mammalian brain as determined by a detergent-based radioimmunoassay.
Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.
Distribution of protein phosphatases-1 alpha and -1 gamma 1 and the D(1) dopamine receptor in primate prefrontal cortex: Evidence for discrete populations of spines.
Diverse psychotomimetics act through a common signaling pathway.
Does insulin dysfunction play a role in Alzheimer's disease?
Dopamine- and adenosine-3',5'-monophosphate (cAMP)-regulated phosphoprotein of 32 kDa (DARPP-32) in the adrenal gland: Immunohistochemical localization.
Dopamine- and adenosine-3':5'-monophosphate (cAMP)-regulated phosphoprotein of Mr 32,000 (DARPP-32) in the retina of cat, monkey and human.
Dopamine and cAMP-Regulated Phosphoprotein 32 kDa Controls Both Striatal Long-Term Depression and Long-Term Potentiation, Opposing Forms of Synaptic Plasticity
Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.
Dopamine- and cAMP-regulated phosphoprotein DARPP-32: Phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin
dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions., A
Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglion.
Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32.
Dopamine D1 agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra.
dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor., A
Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling.
Dopamine Enhancement of NMDA Currents in Dissociated Medium-Sized Striatal Neurons: Role of D1 Receptors and DARPP-32
Dopamine-induced recruitment of dopamine D1 receptors to the plasma membrane
Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra.
Dopamine-sensitive adenyl cyclase: possible role in synaptic transmission.
Dopamine-sensitive adenylate cyclase and protein phosphorylation in the rat caudate nucleus.
Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor".
Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs.
Dopamine-sensitive adenylate cyclase within laminae of the olfactory tubercle.
Dopaminergic regulation of protein phosphorylation in the striatum: DARPP-32.
Drug interactions with cyclic nucleotide and protein phosphorylation systems.
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia
Dual involvement of G-substrate in motor learning revealed by gene deletion
Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus.
effect of formulation on phenmetrazine plasma levels in man studied by a sensitive analytic method., The
Effect of frequency of electrical stimulation on the concentration of intermediary metabolites in mammalian non-myelinated fibres.
Effect of hypophysectomy on liver diphosphopyridine nucleotide: the role of nicotinamide.
Effect of hypophysectomy on pyridine nucleotide metabolism. The role of nicotinamide.
Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice
effect of the nerve sheath on the action of local anesthetics., The
Effects of catecholamines and prostaglandin E1 on cyclic AMP, cation fluxes, and protein phosphorylation in the frog erythrocyte.
Effects of cholera enterotoxin on catecholamine-stimulated changes in cation fluxes, cell volume, and cyclic AMP levels in the turkey erythrocyte.
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
Effects of colchicine on cyclic AMP levels in human leukocytes.
Effects of synapsin I and calcium/calmodulin-dependent protein kinase II on spontaneous neurotransmitter release in the squid giant synapse.
Effects of the neuronal phosphoprotein synapsin I on actin polymerization. I. Evidence for a phosphorylation-dependent nucleating effect.
Effects of the neuronal phosphoprotein synapsin I on actin polymerization. II. Analytical interpretation of kinetic curves.
Emergence of cyclic guanosine 3':5'-monophosphate-dependent protein kinase immunoreactivity in developing rhesus monkey cerebellum: correlative immunocytochemical and electron microscopic analysis.
endogenous substrate for cGMP-dependent protein kinase in mammalian cerebellum., An
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.
Enhanced generation of Alzheimer's amyloid-[beta] following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C
Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C.
Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons.
Enthalpy of hydrolysis of the 3' bond of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate.
enthalpy of hydrolysis of various 3',5'-and 2',3'-cyclic nucleotides., The
Enzyme systems involved in phosphorylation and dephosphorylation of two endogenous phosphoproteins in neuronal membranes.
Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity
Estradiol affects spinophilin protein differently in gonadectomized males and females.
Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice
Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys
Estrogen Lowers Alzheimer beta -Amyloid Generation by Stimulating trans-Golgi Network Vesicle Biogenesis
Estrogen reduces neuronal generation of Alzheimer beta -amyloid peptides
Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein
Estrogen Replacement Increases Spinophilin-immunoreactive Spine Number in the Prefrontal Cortex of Female Rhesus Monkeys
Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism.
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.
Evidence for phosphorylation and oligomeric assembly of presenilin 1.
Evidence for widespread effects of noradrenaline on axon terminals in the rat frontal cortex.
Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase.
Excitatory amino acid antagonists and Parkinson's disease.
Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses.
Expression of APP in brains of transgenic mice containing the entire human APP gene.
Expression of cell-type-specific neuronal phosphoproteins.
Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue.
Expression of synapsin I correlates with maturation of the neuromuscular synapse.
Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain.
FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.
Fifth international conference on cyclic nucleotides and protein phosphorylation, Milan, June 27-July 1, 1983
Forebrain overexpression of CK1 delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD
Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.
Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro.
Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation.
Functional Mouse Retroposed Gene Rps23r1 Reduces Alzheimer's beta -Amyloid Levels and Tau Phosphorylation, A
Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.
Generation and regulation of beta -amyloid peptide variants by neurons
Generation of Alzheimer beta -amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
Generation of the Amyloid- beta Peptide N Terminus in Saccharomyces cerevisiae Expressing Human Alzheimer's Amyloid- beta Precursor Protein
Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model
Gleevec inhibits beta -amyloid production but not Notch cleavage
Glutamate regulates adenylate cyclase and guanylate cyclase activities in an isolated membrane preparation from insect muscle.
Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades
GSK-3-selective inhibitors derived from Tyrian purple indirubins.
Guanosine 3':5'-cyclic monophosphate-dependent phosphorylation of endogenous substrate proteins in membranes of mammalian smooth muscle.
Histamine-sensitive adenylate cyclase in mammalian brain.
Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons.
Hormonal control of protein phosphorylation in turkey erythrocytes. Phosphorylation by cAMP-dependent and Ca2+-dependent protein kinases of distinct sites in goblin, a high molecular weight protein of the plasma membrane.
Hormonal effects on DPN concentration in rat liver.
Hormonally regulated phosphoprotein of turkey erythrocytes: localization to plasma membrane.
Hormone-sensitive adenyl cyclase: cytochemical localization in rat liver.
Hormone-sensitive ion transport systems in erythrocytes as models for epithelial ion pathways.
Identification, characterization, and quantitative measurement of cyclic AMP receptor proteins in cytosol of various tissues using a photoaffinity ligand.
Identification of a dopamine- and 3'5'-cyclic adenosine monophosphate-regulated phosphoprotein of 32 kD (DARPP-32) in parathyroid hormone-producing cells of the human parathyroid gland.
Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene.
Identification of endogenous substrate proteins for cAMP-dependent protein kinase in bovine brain.
Identification of the Alzheimer beta/A4 amyloid precursor protein in clathrin-coated vesicles purified from PC12 cells.
Identification of the cyclic AMP-dependent protein kinase responsible for endogenous phosphorylation of substrate proteins in synaptic membrane fraction from rat brain.
Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM.
Immunocytochemical localization, in synapses, of protein I, an endogenous substrate for protein kinases in mammalian brain.
Immunocytochemical localization of amyloid precursor protein in rat brain.
Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brain.
Immunocytochemical localization of DARPP-32, a dopamine and cyclic-AMP-regulated phosphoprotein, in the primate brain.
Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.
Immunocytochemical localization of the neuron-specific form of the c-src gene product, pp60c-src(+), in rat brain.
Immunohistochemical evidence for the existence of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in brown adipose tissue of pigs.
Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain.
Impaired conditioned taste aversion learning in spinophilin knockout mice.
Impaired recycling of synaptic vesicles after acute perturbation of the presynaptic actin cytoskeleton.
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice
Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice
Improving the quality of immunoblots by chromatography of polyclonal antisera on keratin affinity columns.
Increase in synapsin I phosphorylation implicates a presynaptic component in septal kindling
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling
Increased cyclic GMP levels associated with contraction in muscle fibres of the giant barnacle.
Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins.
Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb.
Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation.
Inhibition by dopamine of (Na(+)+K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism.
Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites.
Inhibition of Mitochondrial Complex II Induces a Long-Term Potentiation of NMDA-Mediated Synaptic Excitation in the Striatum Requiring Endogenous Dopamine
Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
Inhibitor-1 Is Not Required for the Activation of Glycogen Synthase by Insulin in Skeletal Muscle
Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia.
Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.
interaction of colchicine with hormone-sensitive adenylate cyclase in human leukocytes., The
Interaction of free and synaptic vesicle-bound synapsin I with F-actin.
Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.
Interactions of synapsin I with phospholipids: possible role in synaptic vesicle clustering and in the maintenance of bilayer structures.
Intraneuronal Abeta42 accumulation in human brain.
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology.
Introduction of impermeant molecules into synaptosomes using freeze/thaw permeabilization.
Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine.
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine
Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac).
Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice.
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit.
Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles.
Kinetics of G-protein-coupled receptor endosomal trafficking pathways revealed by single quantum dots
l-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice
Laminin and neuropeptide Y are increased by synapsin transfection in cultured NG108-15 neuroblastoma/glioma hybrid cells
Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling.
Localization in mammalian brain of G-substrate, a specific substrate for guanosine 3',5'-cyclic monophosphate-dependent protein kinase.
Localization of ARPP-90, a major 90 kiloDalton basal ganglion-enriched substrate for cyclic AMP-dependent protein kinase, in striatonigral neurons in the rat brain.
Localization of cyclic GMP-dependent protein kinase and substrate in mammalian cerebellum.
Localization of cyclic GMP-dependent protein kinase in rat basal ganglia neurons.
Localization of DARPP-32 immunoreactive neurons in the bed nucleus of the stria terminalis and central nucleus of the amygdala: co-distribution with axons containing tyrosine hydroxylase, vasoactive intestinal polypeptide, and calcitonin gene-related peptide.
Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex
Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain.
Localization of dopamine-sensitive adenylate cyclase activity within laminae of the rat prefrontal cortex.
Localization of synapsin I at the frog neuromuscular junction.
Localization of the MARCKS (87 kDa) protein, a major specific substrate for protein kinase C, in rat brain.
Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia
Lowering beta -Amyloid Levels Rescues Learning and Memory in a Down Syndrome Mouse Model
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
Maintenance of pregnancy in protein-deficient rats by adrenocortical steroid or ACTH administration.
major calmodulin-binding protein common to various vertebrate tissues., A
Mammalian brain phosphoproteins as substrates for calcineurin.
mathematical tool for exploring the dynamics of biological networks, A
Mating-Related Stimulation Induces Phosphorylation of Dopamine- and Cyclic AMP-Regulated Phosphoprotein-32 in Progestin Receptor-Containing Areas in the Female Rat Brain
Mechanism of action of benzodiazepines
Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides.
Mechanism of Regulation of Casein Kinase I Activity by Group I Metabotropic Glutamate Receptors
Mechanisms of Locomotor Sensitization to Drugs of Abuse in a Two-Injection Protocol
Membrane depolarization and carbamoylcholine stimulate phosphatidylinositol turnover in intact nerve terminals.
Metabolic studies on the hyperpolarization following activity in mammalian non-myelinated nerve fibres.
Metabolism of Alzheimer beta -amyloid precursor protein: Regulation by protein kinase A in intact cells and in a cell-free system
Methylphenidate-induced dendritic spine formation and [Delta]FosB expression in nucleus accumbens
Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens.
Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear.
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture.
Microvesicles of the neurohypophysis are biochemically related to small synaptic vesicles of presynaptic nerve terminals.
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.
Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase.
Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.
Molecular determinants of synapsin targeting to presynaptic terminals.
Molecular evolution of the synapsin gene family.
Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells.
Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.
Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum.
Motivational effects of ethanol in DARPP-32 knock-out mice.
Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons.
multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinase., A
Multiple actions of spinophilin regulate mu opioid receptor function.
Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.
Muscarinic cholinergic regulation of cyclic guanosine 3,5-monophosphate in autonomic ganglia: possible role in synaptic transmission.
Mutation of the protein kinase C phosphorylation site on rat alpha1 Na+,K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness.
Na+,K(+)-ATPase in the choroid plexus. Regulation by serotonin/protein kinase C pathway.
Na+,K(+)-ATPase phosphorylation in the choroid plexus: synergistic regulation by serotonin/protein kinase C and isoproterenol/cAMP-PK/PP-1 pathways.
nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes., The
Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19.
Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglion.
Network of Control Mediated by Regulator of Calcium/Calmodulin-Dependent Signaling, A
neurobiology of dopamine signaling., The
neurobiology of slow synaptic transmission., The
neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons, A
Neurogenic effects of fluoxetine are attenuated in p11 (S100A10) knockout mice.
Neuron-specific expression of the synapsin II gene is directed by a specific core promoter and upstream regulatory elements.
Neuron-specific phosphoproteins as models for neuronal gene expression.
Neuron-specific phosphoproteins in mammalian brain.
Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.
Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice.
Neuronal localization of Ca2+-dependent protein phosphorylation in brain.
Neuronal localization of specific brain phosphoproteins.
Neuronal phosphoproteins. Mediators of signal transduction.
Neuronal phosphoproteins: physiological and clinical implications.
Neuronal protein phosphorylation: recent studies concerning protein I, a synapse-specific phosphoprotein.
Neurotensin regulates DARPP-32 Thr34 phosphorylation in neostriatal neurons by activation of dopamine D1-type receptors
Neurotransmitter- and neuromodulator-dependent alterations in phosphorylation of protein I in slices of rat facial nucleus.
Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.
New assay methods for cyclic nucleotides.
Nicotinamide deamidase in Ehrlich ascites tumor cells.
Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons.
Nitric oxide/cGMP pathway stimulates phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, in the substantia nigra.
Norbin Is an Endogenous Regulator of Metabotropic Glutamate Receptor 5 Signaling
novel cyclin provides a link between dopamine and RNA processing., A
novel synaptic vesicle-associated phosphoprotein: SVAPP-120., A
Novel target sites for estrogen action in the dorsal hippocampus: an examination of synaptic proteins.
Nucleotide sequence of a cDNA for the bovine myristoylated alanine-rich C kinase substrate (MARCKS).
On the mechanism of action of cyclic AMP and its role in synaptic transmission.
On the reactivity and mechanism of action of cyclic nucleotides.
On the relative efficacy of nicotinamide and nicotinic acid as precursors of nicotinamide adenine dinucleotide.
Ontogeny of the dopamine and cyclic adenosine-3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the pre- and postnatal mouse central nervous system.
Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum
Ovarian function and morphology after deletion of the DARPP-32 gene in mice.
Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses.
p11 (S100A10) -- an inducible adaptor protein that modulates neuronal functions
Patch-recorded single-channel currents of the purified and reconstituted Torpedo acetylcholine receptor.
PCPP-260, a Purkinje cell-specific cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins
Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.
Pharmacological inhibitors of cyclin-dependent kinases.
Pharmacological inhibitors of glycogen synthase kinase 3.
Pharmacological properties of histamine-sensitive adenylate cyclase from guinea pig cardiac ventricular muscle.
Pharmacological properties of histamine-sensitive adenylate cyclase from mammalian brain.
Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes.
phosphatase cascade by which rewarding stimuli control nucleosomal response, A
Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice
Phosphodiesterase 1B Knock-Out Mice Exhibit Exaggerated Locomotor Hyperactivity and DARPP-32 Phosphorylation in Response to Dopamine Agonists and Display Impaired Spatial Learning
Phospholipase D1 corrects impaired beta APP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons
Phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aaspartate responses, The
phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aspartate responses, The
Phosphoprotein phosphatases from rat cerebral cortex. Subcellular distribution and characterization.
Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.
Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals.
Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.
Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium.
Phosphorylation-dependent Effects of Synapsin IIa on Actin Polymerization and Network Formation
Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm.
Phosphorylation of a single mast cell protein in response to drugs that inhibit secretion.
Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C.
Phosphorylation of Alzheimer beta-amyloid precursor-like proteins.
Phosphorylation of connexin 32, a hepatocyte gap-junction protein, by cAMP-dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II.
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo.
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.
Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine.
Phosphorylation of DARPP-32 at Threonine-34 is Required for Cocaine Action
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.
Phosphorylation of DARPP-32 is regulated by GABA in rat striatum and substantia nigra
Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.
Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5)
Phosphorylation of spinophilin modulates its interaction with actin filaments.
Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.
Phosphorylation of the cystic fibrosis transmembrane conductance regulator.
Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase.
Phosphorylation of the nicotinic acetylcholine receptor by an endogenous tyrosine-specific protein kinase.
Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization.
Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology
Photoaffinity labeling of a guanosine 3':5'-monophosphate-dependent protein kinase from vascular smooth muscle.
Photoaffinity labeling of a protein kinase from bovine brain with 8-azidoadenosine 3',5'-monophosphate.
Phylogenetic survey of proteins related to synapsin I and biochemical analysis of four such proteins from fish brain.
Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.
Physiological Role for Casein Kinase 1 in Glutamatergic Synaptic Transmission
Physiology and pharmacology of cyclic AMP.
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation.
Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters.
Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons
Potentiation of NMDA receptor currents by dopamine D sub(1) receptors in prefrontal cortex
Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex
Preparation and characterization of recombinant protein phosphatase 1.
Presence of calcium/calmodulin-dependent protein kinase II in nerve terminals of rat brain.
Presence of free cyclic AMP receptor protein and regulation of its level by cyclic AMP in neuroblastoma-glioma hybrid cells.
Presence of protein I, a phosphoprotein associated with synaptic vesicles, in cerebellar granule cells.
Presenilin-1 Regulates Intracellular Trafficking and Cell Surface Delivery of [beta]-Amyloid Precursor Protein
Presenilin-1 uses phospholipase D1 as a negative regulator of beta -amyloid formation
Presenilins and gamma-Secretase Inhibitors Affect Intracellular Trafficking and Cell Surface Localization of the gamma-Secretase Complex Components
Prevention and remission by adrenocortical steroids of nicotinamide deficiency disorders and of 6-aminonicotinamide toxicity in rats and dogs.
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease.
Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.
Production of phosphorylation state-specific antibodies.
Protein III, a neuron-specific phosphoprotein: variant forms found in human brain.
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56 delta subunit
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit.
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56δ subunit.
protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth, A
Protein kinase C injection into hippocampal pyramidal cells elicits features of long term potentiation.
Protein kinases and phosphoproteins in the nervous system.
Protein kinases in developing rat brain.
Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.
Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin
Protein phosphatase 1 regulation by inhibitors and targeting subunits.
Protein Phosphatase-1 Regulation in the Induction of Long-Term Potentiation: Heterogeneous Molecular Mechanisms
Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3.
Protein phosphorylation and neuronal function.
Protein phosphorylation in cultured endothelial cells.
Protein phosphorylation in nerve terminals: comparison of calcium/calmodulin-dependent and calcium/diacylglycerol-dependent systems.
Protein phosphorylation in the nervous system
Protein phosphorylation inhibits production of Alzheimer amyloid beta /A4 peptide
Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein.
Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein.
Protein phosphorylation systems in postmortem human brain.
Protein phosphotyrosine in mouse brain: developmental changes and regulation by epidermal growth factor, type I insulin-like growth factor, and insulin.
Proteolytic processing of human amyloid beta protein precursor in insect cells: Major carboxyl-terminal fragment is identical to its human counterpart.
Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19.
Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain.
Purification and characterization of cyclic GMP-dependent protein kinases.
Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
Purification and characterization of protein IIIb, a mammalian brain phosphoprotein.
Quantitation of nerve terminal populations: synaptic vesicle-associated proteins as markers for synaptic density in the rat neostriatum.
Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry.
quantitative dot-immunobinding assay for proteins using nitrocellulose membrane filters., A
Quantitative immunocytochemistry of DARPP-32-expressing neurons in the rat caudatoputamen.
Quantitative labeling of the regulatory subunit of type II cAMP-dependent protein kinase from bovine heart by a photoaffinity analog.
Rapid binding of synapsin I to F- and G-actin. A study using fluorescence resonance energy transfer
Rat DARPP-32: cloning, sequencing, and characterization of the cDNA.
Receptor recruitment: a mechanism for interactions between G protein-coupled receptors.
Recruitment of renal dopamine 1 receptors requires an intact microtubulin network.
Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction.
Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1.
Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail.
Regulated cleavage of the Alzheimer amyloid precursor protein: Molecular and cellular basis
Regulated formation of Golgi secretory vesicles containing Alzheimer beta -amyloid precursor protein
Regulation by cAMP and vasoactive intestinal peptide of phosphorylation of specific proteins in striatal cells in culture.
Regulation by histamine of cyclic nucleotide levels in sympathetic ganglia.
Regulation by steroid hormones of phosphorylation of specific protein common to several target organs.
Regulation by the neuropeptide cholecystokinin (CCK-8S) of protein phosphorylation in the neostriatum
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum
Regulation of Alzheimer's disease amyloid- beta formation by casein kinase I
Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists.
Regulation of APP processing by intra- and intercellular signals.
Regulation of beta -Amyloid Secretion by FE65, an Amyloid Protein Precursor-binding Protein
Regulation of chloride channels by protein kinase C in normal and cystic fibrosis airway epithelia.
Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors
Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A
Regulation of DARPP-32 phosphorylation by Delta9-tetrahydrocannabinol.
Regulation of endogenous phosphorylation of specific proteins in synaptic membrane fractions from rat brain by adenosine 3':5'-monophosphate.
Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.
Regulation of neurotransmitter receptor desensitization by protein phosphorylation.
Regulation of neurotransmitter release by synapsin III.
Regulation of nicotinic acetylcholine receptor phosphorylation in rat myotubes by forskolin and cAMP.
Regulation of NMDA receptor trafficking by amyloid-beta
Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes.
Regulation of phosphorylation of proteins I, IIIa, and IIIb in rat neurohypophysis in vitro by electrical stimulation and by neuroactive agents.
Regulation of phosphorylation of the GluR1 AMPA receptor by dopamine D2 receptors
Regulation of Phosphorylation of the GluR1 AMPA Receptor in the Neostriatum by Dopamine and Psychostimulants In Vivo
Regulation of protein phosphorylation and sodium transport in toad bladder.
Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
Regulation of rat Na+-K+-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA
Regulation of receptor function by protein phosphorylation.
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade
Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways
Regulation of Synaptotagmin I Phosphorylation by Multiple Protein Kinases
Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors.
Regulation of the state of phosphorylation of specific neuronal proteins in mouse brain by in vivo administration of anesthetic and convulsant agents.
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging
Remodeling of cytoskeletal architecture of nonneuronal cells induced by synapsin
renal dopamine system., The
Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation.
Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice.
Restoration by barium of action potentials in sodium-deprived mammalian B and C fibres.
Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens.
Rho-Specific GEF Lfc Interacts with Neurabin and Spinophilin to Regulate Dendritic Spine Morphology, The
role for LYNX2 in anxiety-related behavior, A
role for p11 in the antidepressant action of brain-derived neurotrophic factor., A
Role of adrenoceptors in the regulation of dopamine-DARPP-32 signaling in neostriatal neurons
Role of Calcineurin and Protein Phosphatase-2A in the Regulation of DARPP-32 Dephosphorylation in Neostriatal Neurons
Role of cyclic amp in cell function
Role of cyclic AMP in synaptic transmission in the mammalian peripheral nervous system.
role of DARPP-32 in the actions of drugs of abuse., The
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle.
Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation.
Role of Phosphorylation of Alzheimer's Amyloid Precursor Protein during Neuronal Differentiation
Role of protein phosphorylation in neuronal signal transduction.
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies
Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons
Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.
Second International Conference on Cyclic AMP : Vancouver, British Columbia, Canada, July 8-11, 1974
Selective up-regulation of dopamine D1 receptors in dendritic spines by NMDA receptor activation.
Serine and threonine phosphorylation
Serine phosphorylation of the secreted extracellular domain of APP.
Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus.
Serotonin-sensitive adenylate cyclase in neural tissue and its similarity to the serotonin receptor: a possible site of action of lysergic acid diethylamide.
Serotonin stimulates phosphorylation of protein I in the facial motor nucleus of rat brain.
Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein.
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization
Similarities between protein IIIa and protein IIIb, two prominent synaptic vesicle-associated phosphoproteins.
Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involeved in catalysis and inhibitor binding
Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding
solid-phase assay for the phosphorylation of proteins blotted on nitrocellulose membrane filters., A
Solubilization of a phosphoprotein and its associated cyclic AMP-dependent protein kinase and phosphoprotein phosphatase from synaptic membrane fractions, and some kinetic evidence for their existence as a complex.
Somatostatin-induced phosphorylation of mast cell proteins.
Some relationships between action potential, oxygen consumption and coenzyme content in degenerating peripheral axons
Spatial and temporal regulation of Ca2+/calmodulin-dependent protein kinase II activity in developing neurons.
Spatial relationship of the striatonigral and mesostriatal pathways: double-label immunocytochemistry for DARPP-32 and tyrosine hydroxylase.
Specific inhibition by "loop" diuretics of an anion-dependent Na+ + K+ cotransport system in avian erythrocytes.
Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity.
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors.
Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin.
Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors
Spinophilin regulates Ca super(2+) signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors
Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors
Spinophilin regulates the formation and function of dendritic spines
Spinophilin Stabilizes Cell Surface Expression of alpha sub(2B)-Adrenergic Receptors
Steroid hormones may regulate autophosphorylation of adenosine-3',5'-monophosphate-dependent protein kinase in target tissues.
Stimulation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by some analogs of adenosine 3',5'-monophosphate.
Stimulation of beta -Amyloid Precursor Protein Trafficking by Insulin Reduces Intraneuronal beta -Amyloid and Requires Mitogen-Activated Protein Kinase Signaling
Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein.
Stimulus-dependent myristoylation of a major substrate for protein kinase C.
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology
Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy.
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.
Structural Domains Involved in the Regulation of Transmitter Release by Synapsins
Structure and function of the synapsins.
Studies of the physiological role of specific neuronal phosphoproteins.
Studies on the mechanism of action of cyclic AMP in nervous and other tissues.
Study of autophosphorylation of isoenzymes of cyclic AMP-dependent protein kinases.
Study of the conformation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by fluorescence spectroscopy.
Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase.
Subcellular distribution of adenosine 3',5'-monophosphate-dependent protein kinase in rat brain.
Subcellular Distribution of Neurabin Immunolabeling in Primate Prefrontal Cortex: Comparison with Spinophilin
Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: localization to and within dendritic spines.
Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation.
Subcellular localization of cyclic GMP-dependent protein kinase and its substrates in vascular smooth muscle.
Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture
Synapsin Controls Both Reserve and Releasable Synaptic Vesicle Pools during Neuronal Activity and Short-Term Plasticity in Aplysia
Synapsin dispersion and reclustering during synaptic activity
Synapsin I, a neuron-specific phosphoprotein interacting with small synaptic vesicles and F-actin.
Synapsin I, a phosphoprotein associated with synaptic vesicles: possible role in regulation of neurotransmitter release.
Synapsin I: a review of its distribution and biological regulation.
Synapsin I: A synaptic vesicle-associated neuronal phosphoprotein.
Synapsin I, an actin-binding protein regulating synaptic vesicle traffic in the nerve terminal.
Synapsin I bundles F-actin in a phosphorylation-dependent manner.
Synapsin I in nerve terminals: selective association with small synaptic vesicles.
Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity
Synapsin I is a highly surface-active molecule.
Synapsin I partially dissociates from synaptic vesicles during exocytosis induced by electrical stimulation.
Synapsin I regulates glutamate release from rat brain synaptosomes.
Synapsin Ia, synapsin Ib, protein IIIa, and protein IIIb, four related synaptic vesicle-associated phosphoproteins, share regional and cellular localization in rat brain.
Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles.
Synapsin IIa accelerates functional development of neuromuscular synapses
Synapsin IIa bundles actin filaments.
Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles.
Synapsin IIa: expression in insect cells, purification, and characterization.
Synapsin III: Developmental Expression, Subcellular Localization, and Role in Axon Formation
Synapsin Is a Novel Rab3 Effector Protein on Small Synaptic Vesicles: II. FUNCTIONAL EFFECTS OF THE Rab3A-SYNAPSIN I INTERACTION
synapsins and the regulation of synaptic function., The
Synapsins as major neuronal Ca2+/S100A1-interacting proteins.
Synapsins as mediators of BDNF-enhanced neurotransmitter release
Synapsins as regulators of neurotransmitter release.
Synapsins contain O-linked N-acetylglucosamine.
Synapsins in the vertebrate retina: absence from ribbon synapses and heterogeneous distribution among conventional synapses.
Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I.
Synaptic Vesicle Mobilization Is Regulated by Distinct Synapsin I Phosphorylation Pathways at Different Frequencies
Synaptic vesicle phosphoproteins and regulation of synaptic function.
synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions., A
Synaptic vesicle recycling in synapsin I knock-out mice.
Synaptophysin and synapsin I as tools for the study of the exo-endocytotic cycle.
Synaptophysin (p38) at the frog neuromuscular junction: its incorporation into the axolemma and recycling after intense quantal secretion.
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.
Testosterone reduces neuronal secretion of Alzheimer's beta -amyloid peptides
third member of the synapsin gene family, A
Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.
Three-dimensional architecture of presynaptic terminal cytomatrix.
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1
Time-resolved fluorescence study of the neuron-specific phosphoprotein synapsin I. Evidence for phosphorylation-dependent conformational changes.
Tonically active protein kinase A regulates neurotransmitter release at the squid giant synapse.
Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'.
translational profiling approach for the molecular characterization of CNS cell types., A
Translocation of synapsin I in response to depolarization of isolated nerve terminals.
transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate., The
Tryptophan pyrrolase activity during pregnancy.
Two calcium/calmodulin-dependent protein kinases, which are highly concentrated in brain, phosphorylate protein I at distinct sites.
Two sites of action for synapsin domain E in regulating neurotransmitter release.
Type 1 phosphatase, a negative regulator of cardiac function.
Uptake of tyrosine by rat brain in vivo.
Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals.
Voltage-sensitive calcium channels regulate guanosine 3',5'-cyclic monophosphate levels in neuroblastoma cells.
WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines
Widespread distribution of protein I in the central and peripheral nervous systems.
Widespread distribution of the c-src gene product in nerve cells and axon terminals in the adult rat brain.
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
Yield of oxidative phosphorylation associated with the oxidation of succinate to fumarate.
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Thesis (Ph. D.)--Johns Hopkins University, 1953