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Robert G. Roeder (American biologist)
Robert G. Roeder (Amerikaans bioloog)
Robert G. Roeder (US-amerikanischer Biochemiker)
Roeder, R. G.
Roeder, Robert G.
3' IgH enhancer elements shift synergistic interactions during B cell development
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction.
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo.
Activating Signal Cointegrator 2 Belongs to a Novel Steady-State Complex That Contains a Subset of Trithorax Group Proteins
Activation of class II gene transcription by regulatory factors is potentiated by a novel activity.
Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters.
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
Activator-dependent transcription by mammalian RNA polymerase II: in vitro reconstitution with general transcription factors and cofactors.
Activator-Dependent Transcription from Chromatin In Vitro Involving Targeted Histone Acetylation by p300
adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer., The
Alternative Mechanisms by Which Mediator Subunit MED1/TRAP220 Regulates Peroxisome Proliferator-Activated Receptor gamma -Stimulated Adipogenesis and Target Gene Expression
alternative pathway for transcription initiation involving TFII-I., An
Analysis of structure-function relationships of yeast TATA box binding factor TFIID.
Analysis of the role of TFIIE in basal transcription and TFIIH-mediated carboxy-terminal domain phosphorylation through structure-function studies of TFIIE- alpha
Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.
Anti-IgM antibodies down modulate mu-enhancer activity and OTF2 levels in LPS-stimulated mouse splenic B-cells.
Arabidopsis thaliana contains two genes for TFIID.
Assembly and DNA binding of recombinant Ku (p70/p80) autoantigen defined by a novel monoclonal antibody specific for p70/p80 heterodimers.
B-cell-specific coactivator OCA-B: biochemical aspects, role in B-cell development and beyond.
B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes., The
bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID., A
C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in..., The
CCAAT binding NF-Y--TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes.
cDNA clone encoding Drosophila transcription factor TFIID.
Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription.
cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription., The
Characterization of the core promoter of the Na+/K(+)-ATPase alpha 1 subunit gene. Elements required for transcription by RNA polymerase II and RNA polymerase III in vitro.
Characterization of the highly conserved TFIIA small subunit from Drosophila melanogaster.
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation
Cloning and characterization of a TFIIIC2 subunit (TFIIIC beta ) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors
Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC
Cloning and characterization of human TAF20/15: Multiple interactions suggest a central role in TFIID complex formation
Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III
Cloning and Characterization of Two Evolutionarily Conserved Subunits (TFIIIC102 and TFIIIC63) of Human TFIIIC and Their Involvement in Functional Interactions with TFIIIB and RNA Polymerase III
Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box.
Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B.
Cloning of an Inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1
Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators
Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID.
Cloning of two proximal sequence element-binding transcription factor subunits ( gamma and delta ) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein
Coactivation by OCA-B: Definition of critical regions and synergism with general cofactors
Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases
cofactor, TIP30, specifically enhances HIV-1 Tat activated transcription, A
complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly., The
conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth., The
Conserved sequence motifs in the small subunit of human general transcription factor TFIIE.
Conserved structural motifs between Xenopus and human TFIIB.
Conserved structural motifs within the N-terminal domain of TFIID tau from Xenopus , mouse and human.
Considerations of transcriptional control mechanisms: Do TFIID--core promoter complexes recapitulate nucleosome-like functions?
Control of class II gene transcription during in vitro nucleosome assembly.
Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta.
Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF.
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.
Core promoter-specific function of a mutant transcription factor TFIID defective in TATA-box binding.
Critical role of the second stirrup region of the TATA-binding protein for transcriptional activation both in yeast and human.
Crystal structure of a human TATA box-binding protein/TATA element complex
Crystal structure of a TFIIB-TBP-TATA-element ternary complex.
Crystal Structure of Negative Cofactor 2 Recognizing the TBP-DNA Transcription Complex
Crystal structure of TFIID TATA-box binding protein.
CTD-like sequences are important for transcriptional activation by the proline-rich activation domain of CTF1.
cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors, The
Definition of the transcriptional activation domain of recombinant 43-kilodalton USF.
Different functional modes of p300 in activation of RNA polymerase III transcription from chromatin templates.
Direct association of p300 with unmodified H3 and H4 N termini modulates p300-dependent acetylation and transcription of nucleosomal templates.
Direct binding of yeast transcription factor (TFIID) to the ribosomal protein L32 (rpL32) TATA-less promoter sequence
Direct interaction of human TFIID with the HIV-1 transactivator tat.
Direct interactions of OCA-B and TFII-I regulate immunoglobulin heavy-chain gene transcription by facilitating enhancer-promoter communication.
Direct role for Myc in transcription initiation mediated by interactions with TFII-I
Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer
DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III.
Drosophila 110-kDa transcription factor TFIID subunit directly interacts with the N-terminal region of the 230-kDa subunit., The
Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID.
Drosophila TAF(II)230 and the transcriptional activator VP16 bind competitively to the TATA box-binding domain of the TATA box-binding protein.
Drosophila TAFII230 and the transcriptional activator VP16 bind competitively to the TATA box-binding domain of the TATA box-binding protein.
Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene.
dynamic model for PC4 coactivator function in RNA polymerase II transcription, A
Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation.
E Protein Silencing by the Leukemogenic AML1-ETO Fusion Protein
Effects of activation-defective TBP mutations on transcription initiation in yeast.
Elucidation of three putative structural subdomains by comparison of primary structure of Xenopus and human RAP74.
Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain
Epitopes of the p70 and p80 (Ku) lupus autoantigens.
eukaryotic transcriptional machinery: complexities and mechanisms unforeseen, The
eukaryotic transcriptional machinery, The : complexities and mechanisms unforeseen
Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.
Expression and purification of general transcription factors by FLAG epitope-tagging and peptide elution.
Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG.
Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE.
Family of proteins that interact with TFIID and regulate promoter activity.
Feed-Forward Repression Mechanism Anchors the Sin3/Histone Deacetylase and N-CoR/SMRT Corepressors on Chromatin, A
Functional Analysis of the OCA-B Promoter
Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity.
Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II
GAS41 Is Required for Repression of the p53 Tumor Suppressor Pathway during Normal Cellular Proliferation
Genetic Analyses of NFKB1 and OCA-B Function: Defects in B Cells, Serum IgM Level, and Antibody Responses in Nfkb1 super(-/-) Oca-b super(-/-) Mice
Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor [gamma] Isoforms
Genetic and biochemical analyses of yeast TATA-binding protein mutants.
Genomics and transcription analysis of human TFIID
HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.
helix-loop-helix/leucine repeat transcription factor USF can be functionally regulated in a redox-dependent manner., The
Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer.
high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein, The
Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID).
histone octamer-like structure within TFIID., A
HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.
Human general transcription factor TFIIA: Characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions., The
human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex., The
Human Mediator Enhances Basal Transcription by Facilitating Recruitment of Transcription Factor IIB during Preinitiation Complex Assembly
Human PAD4 regulates histone arginine methylation levels via demethylimination.
Human PAF1 Complex Acts in Chromatin Transcription Elongation Both Independently and Cooperatively with SII/TFIIS, The
human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID., A
Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo
Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells
Human TFIIIC relieves chromatin-mediated repression of RNA polymerase III transcription and contains an intrinsic histone acetyltransferase activity.
Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters.
Identification and characterization of a novel OCA-B isoform. implications for a role in B cell signaling pathways.
Identification of a novel factor that interacts with an immunoglobulin heavy-chain promoter and stimulates transcription in conjunction with the lymphoid cell-specific factor OTF2.
Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition
Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer.
Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.
Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau ).
Identification of TFIID components required for transcriptional activation by upstream stimulatory factor.
Identification of transcription coactivator OCA-B-dependent genes involved in antigen-dependent B cell differentiation by cDNA array analyses.
Identification of two large subdomains in TFIIE-alpha on the basis of homology between Xenopus and human sequences.
Identification of USF as the ubiquitous murine factor that binds to and stimulates transcription from the immunoglobulin lambda 2-chain promoter.
Identity between TRAP and SMCC Complexes Indicates Novel Pathways for the Function of Nuclear Receptors and Diverse Mammalian Activators
Imperfect conservation of a sigma factor-like subregion in Xenopus general transcription factor RAP30.
Independent control of transcription initiations from two sites by an initiator-like element and TATA box in the human c-erbB-2 promoter.
Inhibition of Androgen Receptor-Mediated Transcription by Amino-Terminal Enhancer of split
Initiator element binding protein TFII-I: a tale of two sites.
Interaction between cell cycle regulator, E2F-1, and NF-kappaB mediates repression of HIV-1 gene transcription.
Interaction between the N-terminal domain of the 230-kDa subunit and the TATA box-binding subunit of TFIID negatively regulates TATA-box binding
Interaction of TFIID in the minor groove of the TATA element.
Interaction of the B Cell-specific Transcriptional Coactivator OCA-B and Galectin-1 and a Possible Role in Regulating BCR-mediated B Cell Proliferation
Interaction of the human T-cell lymphotropic virus type 1 Tax transactivator with transcription factor IIA
Interactions of the HIV-1 Tat and RAP74 proteins with the RNA polymerase II CTD phosphatase FCP1.
Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF- Kappa B and Sp1
Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappaB and Sp1.
Involvement of the basic repeat domain of TATA-binding protein (TBP) in transcription by RNA polymerase I, II, and III.
Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action.
Isolation and characterization of a cDNA encoding Drosophila transcription factor TFIIB.
Isolation and functional characterization of the TRAP/mediator complex.
Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation
Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation
Lasker Basic Medical Research Award. The eukaryotic transcriptional machinery: complexities and mechanisms unforeseen.
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
major histocompatibility complex class II Ea promoter requires TFIID binding to an initiator sequence., The
mAM Facilitates Conversion by ESET of Dimethyl to Trimethyl Lysine 9 of Histone H3 to Cause Transcriptional Repression
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein.
Mechanism of Polymerase II Transcription Repression by the Histone Variant macroH2A
MED1/TRAP220 Exists Predominantly in a TRAP/ Mediator Subpopulation Enriched in RNA Polymerase II and Is Required for ER-Mediated Transcription
mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220, The
Mediator-responsive form of metazoan RNA polymerase II, A
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors
MLL associates specifically with a subset of transcriptionally active target genes
Molecular cloning, expression, and characterization of the Drosophila 85-kilodalton TFIID subunit
Molecular cloning of Drosophila TFIID subunits
Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis.
Multiple sequence elements in the c-fos promoter mediate induction by cAMP.
muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism, A
N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2., The
Nontranscriptional Regulation of SYK by the Coactivator OCA-B Is Required at Multiple Stages of B Cell Development
novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors., A
Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAF sub(II)50-containing TFIID complex
Novel Human SRB/MED-Containing Cofactor Complex, SMCC, Involved in Transcription Regulation, A
novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro., A
novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription, A
Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase II
Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III
Nuclear RNA polymerases: role of general initiation factors and cofactors in eukaryotic transcription.
Nucleotide and amino acid sequence of RAP30.
OCA-B integrates B cell antigen receptor-, CD40L- and IL 4-mediated signals for the germinal center pathway of B cell development.
OcaB Is Required for Normal Transcription and V(D)J Recombination of a Subset of Immunoglobulin Kappa Genes
Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes.
Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53.
Overlapping transcription by RNA polymerases II and III of the Xenopus TFIIIA gene in somatic cells
p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1., The
p300 and PCAF Act Cooperatively To Mediate Transcriptional Activation from Chromatin Templates by Notch Intracellular Domains In Vitro
Phosphorylation negatively regulates the function of coactivator PC4.
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
plant DNA-binding protein increases the number of active preinitiation complexes in a human in vitro transcription system., A
Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration
Positive and Negative TAF sub(II) Functions That Suggest a Dynamic TFIID Structure and Elicit Synergy with TRAPs in Activator-Induced Transcription
Potential RNA polymerase II-induced interactions of transcription factor TFIIB.
Principal Role of TRAP/Mediator and SWI/SNF Complexes in Kaposi's Sarcoma-Associated Herpesvirus RTA-Mediated Lytic Reactivation
Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation
Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes.
Purification and characterization of human transcription factor IIIA.
Purification and characterization of two forms of human transcription factor IIIC.
Purification and Identification of a Novel Complex Which Is Involved in Androgen Receptor-Dependent Transcription
Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes.
Purification of a yeast TATA box-binding protein that exhibits human transcription factor IID activity.
Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies.
Purified octamer binding transcription factors stimulate RNA polymerase III--mediated transcription of the 7SK RNA gene.
quick procedure for purification of functional recombinant proteins over-expressed in E.coli., A
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.
Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF.
Recombinant yeast TFIID, a general transcription factor, mediates activation by the gene-specific factor USF in a chromatin assembly assay.
Reconstitution and transcriptional analysis of chromatin in vitro.
Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle.
Regulation of MLL1 H3K4 methyltransferase activity by its core components
Regulation of TFIIH ATPase and kinase activities by TFIIE during active initiation complex formation
Regulation of the p300 HAT domain via a novel activation loop
Repression of HIV-1 transcription by a cellular protein.
Requirement of TRAP/Mediator for Both Activator-Independent and Activator- Dependent Transcription in Conjunction with TFIID-Associated TAF sub(II)s
RNA polymerase II cofactor PC2 facilitates activation of transcription by GAL4-AH in vitro
RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2
role of general and gene-specific coactivators in the regulation of eukaryotic transcription, 1997:, The
Role of general and gene-specific cofactors in the regulation of eukaryotic transcription.
role of general initiation factors in transcription by RNA polymerase II., The
Role of Mediator in Transcriptional Activation by the Aryl Hydrocarbon Receptor
Role of OCA-B in 3'-IgH Enhancer Function
role of transcriptional coactivator TRAP220 in myelomonocytic differentiation, The
Roles of histone H3-lysine 4 methyltransferase complexes in NR-mediated gene transcription.
S Phase Activation of the Histone H2B Promoter by OCA-S, a Coactivator Complex that Contains GAPDH as a Key Component
Sarkosyl defines three intermediate steps in transcription initiation by RNA polymerase III: application to stimulation of transcription by E1A.
Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin.
Sequence of general transcription factor TFIIB and relationships to other initiation factors.
Serum response factor affects preinitiation complex formation by TFIID in vitro.
single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA., A
Specific interactions and potential functions of human TAFII100.
Spermiogenesis deficiency in mice lacking the Trf2 gene
stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements, A
STAGA subunit ADA2b is an important regulator of human GCN5 catalysis., The
Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID).
Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator.
Structural and Functional Organization of TRAP220, the TRAP/Mediator Subunit That Is Targeted by Nuclear Receptors
Structural conservation of putative functional motifs between Xenopus and human TFIIE- beta .
Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE.
Structural organization of yeast and mammalian mediator complexes.
Structural similarity between TAFs and the heterotetrameric core of the histone octamer
Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains
Structure and function of the b/HLH/Z domain of USF
Structure, function and expression of a murine homeobox protein AREC3, a homologue of Drosophila sine oculis gene product, and implication in development.
SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays
Synergistic activation of transcription by CBP and p53.
Synergistic Functions of SII and p300 in Productive Activator-Dependent Transcription of Chromatin Templates
SYT Associates with Human SNF/SWI Complexes and the C-terminal Region of Its Fusion Partner SSX1 Targets Histones
Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
TATA-binding protein-associated factor(s) in TFIID function through the initiator to direct basal transcription from a TATA-less class II promoter.
TATA-binding protein residues implicated in a functional interplay between negative cofactor NC2 (Dr1) and general factors TFIIA and TFIIB.
TATA Box Mimicry by TFIID: Autoinhibition of Pol II Transcription
TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis., The
TFII-I Regulates Induction of Chromosomally Integrated Human Immunodeficiency Virus Type 1 Long Terminal Repeat in Cooperation with USF
TFIIA induces conformational changes in TFIID via interactions with the basic repeat.
TFIIIC1 acts through a downstream region to stabilize TFIIIC2 binding to RNA polymerase III promoters.
TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity., The
Thyroid Hormone-Induced Juxtaposition of Regulatory Elements/Factors and Chromatin Remodeling of Crabp1 Dependent on MED1/TRAP220
Thyroid hormone receptor-associated proteins and general positive cofactors mediate thyroid hormone receptor function in the absence of the TATA box-binding protein-associated factors of TFIID.
TIP30 deficiency increases susceptibility to tumorigenesis.
TIP30 has an intrinsic kinase activity required for up- regulation of a subset of apoptotic genes
TIP30 Interacts with an Estrogen Receptor alpha -interacting Coactivator CIA and Regulates c-myc Transcription
Topology and reorganization of a human TFIID-promoter complex
Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs.
Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.
Transcription factor OTF-1 interacts with two distinct DNA elements in the A gamma-globin gene promoter.
Transcription factor TFIIB sites important for interaction with promoter-bound TFIID.
Transcription factor TFIID induces DNA bending upon binding to the TATA element.
Transcription of in vitro assembled chromatin templates in a highly purified RNA polymerase II system.
Transcriptional activation in yeast by the proline-rich activation domain of human CTF1.
transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression., The
Transcriptional regulation and the role of diverse coactivators in animal cells
Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters.
Transformation by homeobox genes can be mediated by selective transcriptional repression.
TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro, The
TRAP/SMCC/Mediator complex and thyroid hormone receptor function., The
TRAP/SMCC/Mediator-Dependent Transcriptional Activation from DNA and Chromatin Templates by Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4
TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development, The
TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion, The
ts13 mutation in the TAF(II)250 subunit (CCG1) of TFIID directly affects transcription of D-type cyclin genes in cells arrested in G1 at the nonpermissive temperature., The
tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4, A
Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation
unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II., A
Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.
Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression
Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression.
Upstream stimulating factor affects human immunodeficiency virus type 1 (HIV-1) long terminal repeat-directed transcription in a cell-specific manner, independently of the HIV-1 subtype and the core-negative regulatory element
upstream stimulatory factor functionally interacts with the Alzheimer amyloid beta -protein precursor gene, The
upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly., An
USA-Derived Transcriptional Coactivator PC2 Is a Submodule of TRAP/SMCC and Acts Synergistically with Other PCs, The
WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.
Xenopus B1 factor is closely related to the mammalian activator USF and is implicated in the developmental regulation of TFIIIA gene expression., The
Yeast transcription factor IID participates in cell-free transcription of a mammalian ribosomal protein TATA-less promoter.
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CELL -CAMBRIDGE MA-
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
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MOLECULAR AND CELLULAR BIOLOGY
NUCLEIC ACIDS RESEARCH
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