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ISNI: 
0000 0000 8180 2961
Name: 
Prusiner, S. B.
Prusiner, Stanley
Prusiner, Stanley B.
Prusiner, Stanley Ben
Stanley B. Prusiner (Amerikaans arts)
Stanley B. Prusiner (Neurologist, biochemist)
Stanley Ben Prusiner
Stanley Prusiner (biochemik i neurobiolog amerykański, noblista)
Stanley Prusiner (biochimico e neurologo statunitense)
Stanley Prusiner (US-amerikanischer Biochemieer, Neurologe, Nobelpreisträger für Physiologie oder Medizin)
Stenli Pruziner
Στάνλεϋ Προύζινερ
Прузинер, Стенли
Стенли Б. Прузинер
Стенли Прузинер
Стенлі Прузінер
Стэнлі Бен Прузінер
Стэнлі Прузінэр
סטנלי פרוזינר
استنلی پریسینر
ستانلي بروسينر
سٹینلی بی پروسینر
سٹینلی پروسنر
স্টানলি বি প্রুসিনার
スタンリー・B・プルシナー
史坦利·布魯希納
Dates: 
1942-
Creation class: 
article
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author
editor
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DiMauro, Salvatore
ebrary, Inc
Fogel, Robert William
Hadlow, William J.
Kaldy, Pierre
McKinley, Michael P.
National Institutes of Health Affiliation (see also from)
Ridley, Rosalind M.
Rosenberg, Roger N.
Stadtman, Earl R.
United States. Public Health Service. Rocky Mountain Laboratory, Hamilton, Mont
University of California Berkeley Affiliation (see also from)
Titles: 
Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene.
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease.
Affinity-Tagged Miniprion Derivatives Spontaneously Adopt Protease-Resistant Conformations
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
Antibodies specific for native PrP.sup.Sc
Antibodies specific for native PrPsc
Antibodies specific for ungulate PrP
Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
Assembly of natural and recombinant prion protein into fibrils.
Asymptomatic deer excrete infectious prions in faeces.
Ataxia in Prion Protein (PrP)-deficient Mice is Associated with Upregulation of the Novel PrP-like Protein Doppel
Attempts to restore scrapie prion infectivity after exposure to protein denaturants.
Binding of Neural Cell Adhesion Molecules (N-CAMs) to the Cellular Prion Protein
Bioluminescence imaging of A[Beta] deposition in bigenic mouse models of Alzheimer's disease
Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease.
Branched Polyamines Cure Prion-Infected Neuroblastoma Cells
Cell division modulates prion accumulation in cultured cells
Change in the Conformation of Prions Accompanies the Emergence of a New Prion Strain, A
Changes in neuropeptide expression in mice infected with prions.
Chemical Induction of Misfolded Prion Protein Conformers in Cell Culture
Clearance and inhibition of conformationally altered proteins
Clinical Companion to the Molecular and Genetic Basis of Neurological Disease
CNS DEGENERATION CAUSED BY NOVEL PATHOGENS
Colloid formation by drugs in simulated intestinal fluid.
Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans
Conformation-dependent high-affinity monoclonal antibodies to prion proteins.
Conformation of PrP(C) on the cell surface as probed by antibodies.
conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform, A
Conformational transitions in peptides containing two putative alpha -helices of the prion protein
Continuous quinacrine treatment results in the formation of drug-resistant prions.
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells.
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
Cooperative Binding of Dominant-Negative Prion Protein to Kringle Domains
Copper binding to the prion protein: structural implications of four identical cooperative binding sites.
Copper coordination in the full-length, recombinant prion protein.
CORE--ANIMAL CORE
CORE--FACILITIES AND HUMAN TISSUE PROCUREMENT CENTER
CORE--SCIENTIFIC CORE
Creutzfeldt-Jakob disease and scrapie prions.
Cryo-immunogold electron microscopy for prions: toward identification of a conversion site.
Cultured Cell Sublines Highly Susceptible to Prion Infection
Cytosolic Prion Protein in Neurons
DEGENERATIVE NEUROLOGICAL DISEASES
Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse.
Design and construction of diverse mammalian prion strains
Detecting cow, sheep and human prions in a sample and transgenic mice used for same
Detecting Mad Cow Disease
Detecting prions in a sample and prion preparation and transgenic animal used for same
DEVELOPMENT OF ASSAY FOR CREUTZFELDT-JAKOB DISEASE
Developmental expression of PrP in the post-implantation embryo.
Diagnosis of human prion disease
Differences between the Prion Protein and its Homolog Doppel: A Partially Structured State with Implications for Scrapie Formation
Differential inhibition of prion propagation by enantiomers of quinacrine.
Directed Evolution of an Anti-prion Protein scFv Fragment to an Affinity of 1 pM and its Structural Interpretation
Discovery of 2-Aminothiazoles as Potent Antiprion Compounds
Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds
Dominant-Negative Inhibition of Prion Formation Diminished by Deletion Mutagenesis of the Prion Protein
Dominant-negative inhibition of prion replication in transgenic mice
Doppel-induced cerebellar degeneration in transgenic mice.
Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.
Early evidence that a protease-resistant protein is an active component of the infectious prion.
Electron crystallography of the scrapie prion protein complexed with heavy metals.
Elimination of prions by branched polyamines and implications for therapeutics
enzymes of glutamine metabolism based on a symposium held at the 164th national meeting of the American Chemical Society in New York City on August 30-31, 1972, The
Evidence for assembly of prions with left-handed beta -helices into trimers
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
EXPERIMENTAL APPROACHES TO DEGENERATIVE NEUROLOGICAL DIS
EXPERIMENTAL APPROACHES TO NEURODEGENERATIVE DISEASES
Folding of Prion Protein to Its Native alpha -Helical Conformation Is under Kinetic Control
gamma -secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains, A
Generation of antisera to purified prions in lipid rafts.
Genes contributing to prion pathogenesis
Genetic and infectious prion diseases.
Genetics of prion infections.
Genetics of prions.
Glycosylation differences between the normal and pathogenic prion protein isoforms
Health, science, and wealth
High-level expression and characterization of a purified 142-residue polypeptide of the prion protein
Human prion diseases.
Human prion strain selection in transgenic mice.
Human prions and plasma lipoproteins
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
Identification of two prion protein regions that modify scrapie incubation time.
Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form
Immunoglobulins in urine of hamsters with scrapie.
Inactivation of prions by acidic sodium dodecyl sulfate.
Induction of Distinct [URE3] Yeast Prion Strains
Influence of Water, Fat, and Glycerol on the Mechanism of Thermal Prion Inactivation
Inherited prion diseases
Insertion in prion protein gene in familial Creutzfeldt-Jakob disease.
INTERNATIONAL SOCIETY FOR NEUROCHEMISTRY MINISYMPOSIUM
JACOB JAVISTS CENTER OF EXCELLENCE IN NEUROSCIENCE
Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR
Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie
Linkage of prion protein and scrapie incubation time genes.
Local Structural Plasticity of the Prion Protein. Analysis of NMR Relaxation Dynamics
Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?
Madness and memory : the discovery of prions--a new biological principle of disease
Mapping the prion protein using recombinant antibodies
Measuring prions by bioluminescence imaging
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice
Mechanisms of prion protein assembly into amyloid
mémoire et la folie la découverte des prions, un nouveau paradigme biologique
METABOLIC REGULATION OF THE CHOROID PLEXUS
Method of detecting prions in a sample and transgenic animal used for same
Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus
Mimicking dominant negative inhibition of prion replication through structure-based drug design
Models of prion disease
molecular and genetic basis of neurological disease, The
Molecular biology and pathology of scrapie and the prion diseases of humans.
Molecular properties of complexes formed between the prion protein and synthetic peptides
MOLECULAR TRANSGENETICS OF HUMAN PRION DISEASE
MULTIPLE SCLEROSIS AND VIRAL INFECTION OF THE CNS
MULTIPLE SCLEROSIS AND VIRAL INFECTIONS OF THE CNS - SUP
Mutant PrP super(Sc) Conformers Induced by a Synthetic Peptide and Several Prion Strains
Mutant PrPSc conformers induced by a synthetic peptide and several prion strains.
Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease.
Natural and experimental prion diseases of humans and animals.
Natural and synthetic prion structure from X-ray fiber diffraction
neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system., The
NMR STRUCTURES OF RECOMBINANT PRPS
Notch-1 activation and dendritic atrophy in prion disease
Nucleic acid encoding prion protein variant
Pathogenesis, immunobiology, virology, and molecular biology of the spongiform encephalopathies
Pathway Complexity of Prion Protein Assembly into Amyloid
peculiar nature of unfolding of the human prion protein., The
Pharmacokinetics of quinacrine in the treatment of prion disease.
Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells.
Physical studies of conformational plasticity in a recombinant prion protein
Potent inhibition of scrapie prion replication in cultured cells by bis-acridines.
Prion and doppel proteins bind to granule cells of the cerebellum
Prion clearance in bigenic mice
Prion detection by an amyloid seeding assay
Prion diseases and neurodegeneration.
Prion diseases of humans and animals
prion diseases., The
prion folding problem, The
Prion Glycoprotein: Structure, Dynamics, and Roles for the Sugars
Prion infection of mouse neurospheres
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
Prion protein biology
Prion protein gene variation among primates.
Prion protein isoforms, a convergence of biological and structural investigations
Prion Protein of 106 Residues Creates an Artificial Transmission Barrier for Prion Replication in Transgenic Mice
Prion protein peptides induce alpha -helix to beta -sheet conformational transitions
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform
Prion protein selectively binds copper(II) ions
Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations.
Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease.
Prion proteins with pathogenic and protective mutations show similar structure and dynamics.
Prions and Neurodegenerative Diseases
Prions causing scrapie and Creutzfeldt-Jakob disease, 1987:
Prions in skeletal muscle
Prions, prions, prions
Prions: So many fibers, so little infectivity
Propagation of prion strains through specific conformers of the prion protein
Proposed three-dimensional structure for the cellular prion protein.
protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice., A
Protease-Sensitive Synthetic Prions
PURIFICATION AND MOLECULAR STRUCTURE OF THE SCRAPIE AGENT
Quantitative trait loci affecting prion incubation time in mice.
QUINACRINE IS MAINLY METABOLIZED TO MONO-DESETHYL QUINACRINE BY CYP3A4/5 AND ITS BRAIN ACCUMULATION IS LIMITED BY P-GLYCOPROTEIN
Recombinant scrapie-like prion protein of 106 amino acids is soluble
REGULATION AND FUNCTION OF BRAIN -GLUTAMYL TRANSPEPTIDA
REGULATION AND FUNCTION OF BRAIN-GLUTAMYL TRANSPEPTIDASE
REGULATION/FUNCTION--BRAIN GAMMA-GLUTAMYL TRANSPEPTIDASE
Resistance of Bovine Spongiform Encephalopathy (BSE) Prions to Inactivation
Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein.
Scrapie prions: a three-dimensional model of an infectious fragment.
Search for a Prion-Specific Nucleic Acid
Selective precipitation of prions by polyoxometalate complexes.
Self-Assembly of Recombinant Prion Protein of 106 Residues
SEN JACOB JAVITS CENTER OF EXCELLENCE IN NEUROSCIENCE
Separation of scrapie prion infectivity from PrP amyloid polymers
Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.
SLOW BRAIN DISEASE: ASSAY AND PURIFICATION OF SCRAPIE
Slow transmissible diseases of the nervous system
Small-molecule aggregates inhibit amyloid polymerization
Sodium dodecyl sulfate compositions for inactivating prions
Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L).
Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration
Soluble form of PrP.sup.SC which is insoluble in native form
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform
Solution Structure of Syrian Hamster Prion Protein rPrP(90-231)
Some strategies and methods for the study of prions
Sponatneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
Spontaneous neurodegeneration in transgenic mice with mutant prion protein.
Strain-specified characteristics of mouse synthetic prions
Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form.
Structural studies of the scrapie prion protein by electron crystallography
Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.
Structure of the recombinant full-length hamster prion protein PrP(29-231): The N terminus is highly flexible
Structures of prion proteins and conformational models for prion diseases.
Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein
Survey of Antiprion Compounds Reveals the Prevalence of Non-PrP Molecular Targets., A
Synthetic mammalian prions.
Synthetic Peptide Initiates Gerstmann-Straeussler-Scheinker (GSS) Disease in Transgenic Mice, A
synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice., A
Theoretical studies of sequence effects on the conformational properties of a fragment of the prion protein: implications for scrapie formation.
Thermodynamics of Model Prions and its Implications for the Problem of Prion Protein Folding
Thioaptamer Interactions with Prion Proteins: Sequence-specific and Non-specific Binding Sites
three-dimensional structure of prion protein: implications for prion disease., The
Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues
Trafficking of prion proteins through a caveolae-mediated endosomal pathway
TRANSGENETICS OF CHIMERIC PROTEINS IN PRION REPLICATION & DISEASE
Transgenic animals expressing artificial epitope-tagged proteins
Transgenic mouse brains for the evaluation and quality control of BSE tests.
TRANSGENIC STUDIES OF SCRAPIE 'STRAINS' AND CNS DEGENERATION BY MUTANT PRP GENES
TRANSMISSIBLE AND GENETIC NEURODEGENERATIVE DISEASES
TRANSMISSIBLE AND GENETIC NEURODENGENERATIVE DISEASES
Transmission and Detection of Prions in Feces
Transmission Barriers for Bovine, Ovine, and Human Prions in Transgenic Mice
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
Transmission of elk and deer prions to transgenic mice.
Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein.
TRANSPORT SYSTEMS OF THE CHOROID PLEXUS
Two different neurodegenerative diseases caused by proteins with similar structures
UNCONVENTIONAL TRANSMISSIBLE AGENTS IN DEGENERATIVE CNS DISEASES
UNCOVENTIONAL TRANSMISSIBLE AGENTS IN DEGENERATIVE CNS DISEASES
When sporadic disease is not sporadic: the potential for genetic etiology.
γ-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains., A
Contributed to or performed: 
ARCHIVES OF NEUROLOGY -CHICAGO-
BRAIN PATHOLOGY -ZURICH-
JOURNAL- AMERICAN CHEMICAL SOCIETY
JOURNAL- ROYAL COLLEGE OF PHYSICIANS OF LONDON
PROCEEDINGS- NATIONAL ACADEMY OF SCIENCES USA
SCIENTIFIC AMERICAN -AMERICAN EDITION-
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