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0000 0000 8183 1981
David Nutt (British activist)
Nutt, D. J.
Nutt, David J.
Ballenger, James C.
Everitt, Barry J.
Lister, Richard G.
Oxford University 1983
Robbins, Trevor W.
Zohar, Joseph (1948-...)
久保木, 富房 (1945-)
2-(4,5-dihydro-1H-imidazol-2-yl)indazole (indazim) derivatives as selective I(2) imidazoline receptor ligands.
2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I sub(2)/adrenergic alpha sub(2) receptor ligands
2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic alpha2 receptor ligands.
3-(Methoxycarbonyl)-amino-beta-carboline reduces both the sedative and anticonvulsant effects of diazepam.
[3H]2-(2-benzofuranyl)-2-imidazoline: a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors.
5-HT3 antagonist ondansetron reduces gastrointestinal side effects induced by a specific serotonin re-uptake inhibitor in man, The
5-HT3 receptors, nausea, and serotonin reuptake inhibition.
5-Isothiocyanato-2-benzofuranyl-2-imidazoline (BU99006) an irreversible imidazoline sub(2) binding site ligand: in vitro and in vivo characterisation in rat brain
Abstinence symptoms after withdrawal of tranquillising drugs: is there a common neurochemical mechanism?
Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling.
Acute Carbon Dioxide Exposure in Healthy Adults: Evaluation of a Novel Means of Investigating the Stress Response
Acute tryptophan depletion alters gastrointestinal and anxiety symptoms in irritable bowel syndrome.
Acute tryptophan depletion. Part I: rationale and methodology
Acute tryptophan depletion. Part II: clinical effects and implications
Addiction : brain mechanisms and their treatment implications
Addiction: the clinical interface
Adenosine Receptor Subtypes Modulate Two Major Functional Pathways for Hippocampal Serotonin Release
Aggressive thoughts and behavior: another symptom of panic disorder?
Alcohol alternatives - a goal for psychopharmacology?
Alcohol and the brain. Pharmacological insights for psychiatrists.
Alcoholism and panic disorder: is the comorbidity more than coincidence?
Alpha 2-adrenoceptor antagonists block the stimulant effects of cocaine in mice.
Alpha-2-adrenoceptor control of cortisol and ACTH in normal volunteers: preliminary open trial of the effects of acute and chronic idazoxan.
Alpha-2-adrenoceptor function in alcohol withdrawal: a pilot study of the effects of iv. clonidine in alcoholics and normals.
Altered central alpha 2-adrenoceptor sensitivity in panic disorder.
Amphetamine misuse and social phobia
Analysis of dynamic radioligand displacement or "activation" studies
Anhedonia and chronic mild stress model in depression.
Antagonist-agonist combinations as therapies for heroin addiction : back to the future?
Antagonizing the anticonvulsant effect of ethanol using drugs acting at the benzodiazepine/GABA receptor complex.
Anticonvulsant activity of the imidazoline 6,7-benzoidazoxan.
Antidepressant drugs and the cardiovascular system: a comparison of tricylics and selective serotonin reuptake inhibitors and their relevance for the treatment of psychiatric patients with cardiovascular problems
Antidepressant-Induced Jitteriness/Anxiety Syndrome: Systematic Review
Antidepressants in panic disorder: clinical and preclinical mechanisms.
Antisense oligonucleotides in psychopharmacology and behaviour: promises and pitfalls.
Anxiety and OCD--the chicken or the egg?
Anxiety - bridging the heart/mind divide
Anxiety disorders comorbid with depression : panic disorder and agoraphobia
Anxiety disorders : generalized anxiety disorder, obsessive-compulsive disorder and post-traumatic stress disorder
Are 5-HT receptors or beta-adrenoceptors involved in idazoxan-induced food and water intake?
Assessment of GABA(A)benzodiazepine receptor (GBzR) sensitivity in patients on benzodiazepines.
Assessment of GABA sub(A) Benzodiazepine Receptor (GBzR) Sensitivity in Patients with Alcohol Dependence
Assessment of GABAA benzodiazepine receptor (GBzR) sensitivity in patients with alcohol dependence.
Association of short alleles of a VNTR of the serotonin transporter gene with anxiety symptoms in patients presenting after deliberate self harm.
Association of the Anxiogenic and Alerting Effects of Caffeine with ADORA2A and ADORA1 Polymorphisms and Habitual Level of Caffeine Consumption
Atlas of psychiatric pharmacotherapy
Attenuation of ethanol intoxication by alpha-2 adrenoceptor antagonists.
Attenuation of the behavioural effects of ethanol in mice by des-enkephalin-gamma-endorphin (ORG 5878).
Autonomic dysregulation and the Window of Tolerance model of the effects of complex emotional trauma
Autoradiographical and behavioural effects of a chronic infusion of antisense to the alpha2D-adrenoceptor in the rat.
Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice
Autoradiography of I2 receptors in frog brain.
Behavioral and cardiovascular effects of 7.5% CO2 in human volunteers
Behavioral and endocrine responses to clomipramine in panic disorder patients with or without alcoholism.
Behavioral and neuroendocrine responses to m-chlorophenylpiperazine in subtypes of alcoholics and in healthy comparison subjects.
Behavioral, neuroendocrine, and cardiovascular response to flumazenil: no evidence for an altered benzodiazepine receptor sensitivity in panic disorder.
Behavioral, neuroendocrine and neurochemical effects of the imidazoline I sub(2) receptor selective ligand BU224 in naive rats and rats exposed to the stress of the forced swim test
Behavioral, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naive rats and rats exposed to the stress of the forced swim test.
Behavioural and physiological effects induced by an infusion of antisense to alpha(2D)-adrenoceptors in the rat.
benzodiazepine agonist and contragonist have hypothermic effects in rodents., A
benzodiazepine antagonist, Ro 15-1788 does not decrease ethanol withdrawal convulsions in rats., The
Benzodiazepine receptor function in anxiety disorders.
Benzodiazepine receptor inverse agonists, 1994:
Benzodiazepine-receptor mediated convulsions in infant rats: effects of beta-carbolines.
Benzodiazepine receptor sensitivity in panic disorder.
Benzodiazepine site pharmacokinetic/pharmacodynamic quantification in man: Direct measurement of drug occupancy and effects on the human brain in vivo
Benzodiazepines, plasma MHPG and alpha-2-adrenoceptor function in man.
beta-carboline binding to imidazoline receptors.
Beyond psychoanaleptics - can we improve antidepressant drug nomenclature?
Bidirectional effects of chronic treatment with agonists and inverse agonists at the benzodiazepine receptor.
biological, social and clinical bases of drug addiction: commentary and debate., The
Blockade of alcohol's amnestic activity in humans by an alpha5 subtype benzodiazepine receptor inverse agonist.
Body temperature discriminates between full and partial benzodiazepine receptor agonists.
Brain dopamine response in human opioid addiction
Brain function in social anxiety disorder.
Brain imaging studies in human addicts.
Brain mechanisms of social anxiety disorder.
Brain mechanisms of social anxiety disorders
Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: an [11C]diprenorphine PET study.
Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: An [ super(11)C]diprenorphine PET study
Brain opioid receptor binding in early abstinence from opioid dependence: positron emission tomography study.
Brief report: Is the association of hypertension and panic disorder explained by clustering of autonomic panic symptoms in hypertensive patients?
British association for psychopharmacology consensus on the treatment of bipolar disorder
British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders
BU98008, a highly selective imidazoline(1)-receptor ligand.
Buprenorphine-cocaine interactions in mice: effect on locomotor activity and hole-dipping behaviour.
Caffeine and central noradrenaline: Effects on mood, cognitive performance, eye movements and cardiovascular function
Calming the brain benzodiazepines and related drugs from laboratory to clinic
Cannabis antagonists : a new era of social psychopharmacology?
Cape Town consensus on posttraumatic stress disorder.
Carbamazepine retards the development of cocaine-kindled seizures but not sensitization to cocaine-induced hyperactivity.
Cardiac slowing and acute tryptophan depletion: a comment on the paper by van der Veen et al.
cardiovascular and subjective effects of thyrotropin releasing hormone (TRH) and a stable analogue, dimethyl proline-TRH, in healthy volunteers., The
Care of depressed patients with anxiety symptoms.
Central alpha-2 adrenoceptors are responsible for a clonidine-induced cue in a rat drug discrimination paradigm.
Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide.
cerebrospinal fluid study of the pathophysiology of panic disorder associated with alcoholism., A
Challenge tests: assessment of the noradrenergic and GABA systems in depression and anxiety disorders.
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Changes in caffeine seizure threshold after electroconvulsive shock.
Changes in regional cerebral blood flow elicited by craving memories in abstinent opiate-dependent subjects.
Characterisation and localisation of [3H]2-(2-benzofuranyl)-2-imidazoline binding in rat brain: a selective ligand for imidazoline I2 receptors.
Characterisation of imidazoline I sub(2) binding sites in pig brain
Characterisation of imidazoline I2 binding sites in pig brain.
Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption
Characterization and autoradiographical localization of non-adrenoceptor idazoxan binding sites in the rat brain.
Characterization of [(3)H]harmane binding to rat whole brain membranes.
Chest pain: panic attack or heart attack?
Chronic benzodiazepine treatment increases the effects of the inverse agonist FG7142.
Chronic electroconvulsive shock and neurotransmitter receptors--an update.
Circadian rhythms of cortisol during alcohol withdrawal.
Clinical correlates of benzodiazepine receptor function.
Clinical Evidence and Potential Neurobiological Underpinnings of Unresolved Symptoms of Depression
Clinical pharmacology of anxiolytics and antidepressants: a psychopharmacological perspective.
Clonidine in alcohol withdrawal: a pilot study of differential symptom responses following i.v. clonidine.
cognitive dysfunction in anxiety and its amelioration by effective treatment with SSRIs, A
Cognitive processing in post-traumatic stress disorder.
Comparison of Alterations in c-fos and Egr-1 (zif268) Expression Throughout the Rat Brain Following Acute Administration of Different Classes of Antidepressant Compounds
comparison of calcium antagonists and diazepam in reducing ethanol withdrawal tremors., A
Comparison of crude methanolic CDS extracts from various tissues.
comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO(2) models of experimental human anxiety., A
Comparison of the effects of benzodiazepine and beta-carboline inverse agonists on body temperature in mice.
Comparison of the effects of chronic desmethylimipramine administration on alpha 2- and beta-adrenoceptors in different regions of rat brain.
comparison of the effects of phenelzine treatment with moclobemide treatment on cardiovascular reflexes., A
Comparison of the effects of repeated electroconvulsive shock on alpha 2- and beta-adrenoceptors in different regions of rat brain.
Consensus statement and research needs: the role of dopamine and norepinephrine in depression and antidepressant treatment.
Consensus statement of posttraumatic stress disorder: From the international consensus group on depression and anxiety
Consensus statement on depression, anxiety, and cardiovascular disease.
Consensus statement on depression, anxiety, and functional gastrointestinal disorders.
Consensus statement on depression, anxiety, and oncology.
Consensus statement on generalized anxiety disorder from the International Consensus Group on depression and anxiety
Consensus statement on panic disorder from the International Consensus Group on Depression and Anxiety.
Consensus statement on social anxiety disorder from the International Consensus Group on depression and anxiety
Consensus statement on the benefit to the community of ESEMeD (European Study of the Epidemiology of Mental Disorders) survey data on depression and anxiety.
Consensus statement on the primary care management of depression from the International Consensus Group on depression and anxiety
Consensus statement on transcultural issues in depression and anxiety from the International Consensus Group on depression and anxiety
Consensus statement update on posttraumatic stress disorder from the international consensus group on depression and anxiety.
Correlation of subjective and objective sleep measurements at different stages of the treatment of depression.
criteria of Cloninger et al. and von Knorring et al. for subgrouping alcoholics: a comparison in a clinical population., The
Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder
Current and former ecstasy users report different sleep to matched controls: a web-based questionnaire study
Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis: disease mechanisms, a diagnostic test and specific treatments.
Cyproterone to treat aggressivity in dementia: a clinical case and systematic review
Cytokine levels in euthymic bipolar patients
d-Cycloserine and performance under different states of anxiety in healthy volunteers
Death and dependence : current controversies over the selective serotonin reuptake inhibitors
Death by tricyclic : the real antidepressant scandal?
Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study.
Demonstration of clomipramine and venlafaxine occupation at serotonin reuptake sites in man in vivo
Dependence on benzodiazepines
Depleting serotonin enhances both cardiovascular and psychological stress reactivity in recovered patients with anxiety disorders.
depressed man requesting St John's wort., A
Desipramine binding to noradrenaline reuptake sites in cardiac sympathetic neurons in man in vivo.
Development and validation of the Generalized Anxiety Disorder Inventory (GADI).
Development of a rational scale to assess the harm of drugs of potential misuse.
Diazepam alters brain 5-HT function in man: implications for the acute and chronic effects of benzodiazepines.
Diazepam and Ro 15-1788 increase absence epilepsy in WAG/Rij rats chronically exposed to diazepam.
Differential effects of selective mu-, kappa- and delta-opioid antagonists on electroshock seizure threshold in mice.
Discontinuation of Vioxx.
Discriminative stimulus properties of ethoxy idazoxan
Distribution of [(3)H]BU224, a selective imidazoline I(2) binding site ligand, in rat brain.
Disturbances of hypothalamic-pituitary-adrenal axis functioning during ethanol withdrawal in six men.
Dizziness produced by a potent 5HT(1A) receptor agonist (eptapirone) is not due to postural hypotension.
Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine
Does alcohol increase the risk of overdose death: the need for a translational approach
Does the brain noradrenaline network mediate the effects of the CO2 challenge?
Dopamine and social anxiety disorder.
Dopamine transporter binding in females with panic disorder may vary with clinical status
Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants
Dr Shipman's last legacy : e-surveillance of the medical profession
Drug harms in the UK: a multicriteria decision analysis.
Drug treatment of chronic insomnia -- dawn at the end of a long night?
Drugs and the future brain science, addiction and society
Early onset anxiolytic efficacy after a single dose of pregabalin: double-blind, placebo- and active-comparator controlled evaluation using a dental anxiety model
ECNP position paper on social phobia proceedings from an ECNP workshop in Jerusalem, October 1994.
effect of 1-(4,5-dihydro-1H-imidazol-2-yl) isoquinoline on monoamine release and turnover in the rat frontal cortex., The
effect of acute and chronic electroconvulsive shock on [3H]phorbol-dibutyrate binding to rat brain membranes., The
Effect of benzodiazepine and beta-carboline antagonists and partial agonists on loprazolam- and ZK 93423-induced hypothermia.
Effect of chloride or glucose on the incidence of lactate-induced panic attacks.
effect of clonidine on plasma MHPG: evidence against tonic alpha 2-adrenoceptor control of noradrenergic function., The
effect of diazepam on indices of 5-HT function in man., The
effect of intravenous flumazenil on interictal electroencephalographic epileptic activity: results of a placebo-controlled study., The
effect of lithium on 5-HT-mediated neuroendocrine responses and platelet 5-HT receptors., The
effect of nicotine on striatal dopamine release in man: A [11C]raclopride PET study, The
Effect of Pregnancy on Panic Attacks
effect of repeated electroconvulsive shock on the function of THIP, a GABA agonist., The
Effect of single and repeated electroconvulsive shock on the hypothalamic-pituitary-adrenal axis and plasma catecholamines in rats.
Effect of the cyclopyrrolones suriclone and RP 59037 on body temperature in mice.
effect of the imidazodiazepine Ro 15-4513 on the anticonvulsant effects of diazepam, sodium pentobarbital and ethanol., The
Effects of 5 weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood
Effects of 7.5% CO(2) inhalation on allocation of spatial attention to facial cues of emotional expression.
Effects of 7.5% CO^sub 2^ challenge in generalized anxiety disorder
Effects of 7.5% CO2 challenge in generalized anxiety disorder.
Effects of acute and chronic electroconvulsive shock on noradrenaline release in the rat hippocampus and frontal cortex.
Effects of acute tryptophan depletion in serotonin reuptake inhibitor-remitted patients with generalized anxiety disorder
Effects of acute tyrosine/phenylalanine depletion on the selective processing of smoking-related cues and the relative value of cigarettes in smokers
Effects of benzodiazepine receptor inverse agonists on locomotor activity and exploration in mice.
Effects of bupropion augmentation in escitalopram-resistant patients with major depressive disorder: an open-label, naturalistic study.
Effects of chronic alpha 2-adrenoceptor blockade on platelet and lymphocyte adrenoceptor binding in normal volunteers.
effects of chronic ritanserin treatment on sleep and the neuroendocrine response to L-tryptophan., The
Effects of chronic treatment with benzodiazepine receptor ligands on cortical adrenoceptors.
effects of clonidine on cardiovascular responses to standing in healthy volunteers., The
Effects of contextual priming on reactions to craving and withdrawal stimuli in alcohol-dependent participants.
effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142., The
effects of electroconvulsive therapy on plasma insulin and glucose in depression., The
effects of idazoxan and other alpha 2-adrenoceptor antagonists on food and water intake in the rat., The
effects of idazoxan and other alpha 2-adrenoceptor antagonists on urine output in the rat., The
effects of idazoxan on reaction times, eye movements and the mood of healthy volunteers and patients with upper respiratory tract illnesses, The
effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy., The
effects of single dose anxiolytic medication on the CO2 models of anxiety: differentiation of subjective and objective measures, The
Effects of stressful life events, maternal depression and 5-HTTLPR genotype on emotional symptoms in pre-adolescent children.
Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers
Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers
Efficacy of mirtazapine in clinically relevant subgroups of depressed patients.
Electroconvulsive shock (ECS) and the adenosine neuromodulatory system: effect of single and repeated ECS on the adenosine A1 and A2 receptors, adenylate cyclase, and the adenosine uptake site.
Emotional symptoms in children: The effect of maternal depression, life events, and COMT genotype.
Endocrine response to syncope in panic disorder.
Endogenous beta-carbolines as clonidine-displacing substances.
Endogenous indoleamines demonstrate moderate affinity for I2 binding sites.
Endogenous opioids may be involved in idazoxan-induced food intake.
Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions--I. The effects of single and repeated bicuculline-induced seizures.
Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions--II. The effects of anaesthesia and current conditions on the appearance of enhanced responses following electroconvulsive shock.
entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs, The
Equasy-- an overlooked addiction with implications for the current debate on drug harms.
Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls
Establishing non-inferiority in treatment trials in psychiatry - guidelines from an Expert Consensus Meeting
Estimating the synaptic concentration of norepinephrine in dentate gyrus which produces beta-receptor mediated long-lasting potentiation in vivo using microdialysis and intracerebroventricular norepinephrine.
Estimation of endogenous noradrenaline release in rat brain in vivo using [3H]RX 821002
Ethanollike properties of the serotonergic partial agonist m-chlorophenylpiperazine in chronic alcoholic patients.
Ethyl beta-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats.
Evaluation in rat of RS-79948-197 as a potential PET ligand for central alpha 2-adrenoceptors.
Evaluation of actigraphy and automated telephoned questionnaires to assess hypnotic effects in insomnia.
Evaluation of [O-methyl-11C]RS-15385-197 as a positron emission tomography radioligand for central alpha2-adrenoceptors.
Evaluation of severe insomnia in the general population--implications for the management of insomnia: the UK perspective.
Evaluation of severe insomnia in the general population: results of a European multinational survey.
Evidence-based guidelines for management of attention-deficit/hyperactivity disorder in adolescents in transition to adult services and in adults: recommendations from the British Association for Psychopharmacology
Evidence-based guidelines for the pharmacological management of substance misuse, addiction and comorbidity: recommendations from the British Association for Psychopharmacology.
Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology
Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 1993 British Association for Psychopharmacology guidelines. British Association for Psychopharmacology.
experimental pharmacology of anxiety, The ; new concepts of benzodiazepine receptor function
Exploring delta-receptor function using the selective opioid antagonist naltrindole.
Exploring the pharmacology of the pro-convulsant effects of alpha 2-adrenoceptor antagonists in mice.
Extraction of active clonidine-displacing substance from bovine lung and comparison with clonidine-displacing substance extracted from other tissues.
feasibility of abrupt methadone--buprenorphine transfer in British opiate addicts in an outpatient setting, The
Flumazenil in alcohol withdrawal: a double-blind placebo-controlled study.
Flumazenil provocation of panic attacks. Evidence for altered benzodiazepine receptor sensitivity in panic disorder.
Foresight brain science, addiction and drugs project.
Functional connectivity analysis of the neural circuits of opiate craving: "more" rather than "different"?
Functional studies of specific imidazoline-2 receptor ligands.
Future directions in substance dependence research.
GABA-A receptors and the response to CO(2) inhalation - a translational trans-species model of anxiety?
GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study
GABA-benzodiazepine receptor function in alcohol dependence: a combined super(11)C-flumazenil PET and pharmacodynamic study
GABAA receptors: subtypes, regional distribution, and function.
GABAB receptors in addiction and its treatment.
GABAergic control of novelty stress-responsive epigenetic and gene expression mechanisms in the rat dentate gyrus.
Gamma hydroxy butyrate abuse and dependency
Gender differences in brain serotonin transporter availability in panic disorder
Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis.
Generalized anxiety disorder: A comorbid disease.
Generalized anxiety disorder: comorbidity, comparative biology and treatment
Generalized anxiety disorder: diagnosis, treatment and its relationship to other anxiety disorders
Generalized anxiety disorder : symptomatology, pathogenesis and management
GENetic and clinical predictors of treatment response in depression: the GenPod randomised trial protocol.
Glutamate and cortisol-a critical confluence in PTSD?
Government vs science over drug and alcohol policy.
Harmane and harmalan are bioactive components of classical clonidine-displacing substance.
Harms associated with psychoactive substances: findings of the UK National Drug Survey.
Highlights of the international consensus statement on major depressive disorder.
Home cage presentation of complex discrimination tasks to marmosets and rhesus monkeys.
Human functional neuroimaging connectivity research in dependence.
Human Taste Thresholds Are Modulated by Serotonin and Noradrenaline
Hypophysectomy alters both 5-hydroxytryptamine- and alpha 2-adrenoceptor-mediated behavioural changes in the rat.
Hypophysectomy does not prevent the enhanced monoamine-mediated behavioural responses following repeated electroconvulsive shocks.
hypothermic response to clonidine is absent in alcohol withdrawal but returns in abstinence., The
Hypothermic responses to infection are inhibited by alpha2-adrenoceptor agonists with possible clinical implications.
Idazoxan-induced reductions in cortical glucose use are accompanied by an increase in noradrenaline release: complementary [14C]2-deoxyglucose and microdialysis studies.
Identification of an I(2) binding protein from rabbit brain.
Identification of an imidazoline binding protein: creatine kinase and an imidazoline-2 binding site.
Identification of ligands selective for central I2-imidazoline binding sites.
Imagery of craving in opiate addicts undergoing detoxification.
Imaging alcohol cue exposure in alcohol dependence using a PET 15O-H2O paradigm: results from a pilot study.
Imaging the GABA-Benzodiazepine Receptor Subtype Containing the [alpha]5-Subunit In Vivo With [11C]Ro15 4513 Positron Emission Tomography
Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography.
Imidazoline(2) (I(2)) binding site- and alpha(2)-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis.
Imidazoline binding sites in Huntington's and Parkinson's disease putamen.
Imidazoline2 (I2) Receptor- and alpha 2- Adrenoceptor-Mediated Modulation of Hypothalamic-Pituitary-Adrenal Axis Activity in Control and Acute Restraint Stressed Rats
Imidazoline2 (I2) receptor- and alpha2-adrenoceptor-mediated modulation of hypothalamic-pituitary-adrenal axis activity in control and acute restraint stressed rats.
Impulsiveness and the prolactin response to d-fenfluramine.
Impulsiveness, serotonin genes and repetition of deliberate self-harm (DSH).
In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain.
In vitro and ex vivo distribution of [ super(3)H]harmane, an endogenous beta -carboline, in rat brain
In vitro and in vivo approaches to the characterization of the alpha2-adrenoceptor.
In vitro and in vivo effect of BU99006 (5-isothiocyanato-2-benzofuranyl-2-imidazoline) on I2 binding in relation to MAO: evidence for two distinct I2 binding sites.
In vivo estimation of imidazoline(2) binding site turnover.
Increased central alpha 2-adrenoceptor sensitivity in panic disorder.
Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome
Increased sexual function in benzodiazepine withdrawal.
Increased sympathetic response to standing in panic disorder.
Infecting the brain to stop addiction?
Informed consent - a new approach to drug regulation?
Inhalation of 35% CO(2) results in activation of the HPA axis in healthy volunteers.
Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites.
Inhibition of baclofen-induced hypothermia in mice by the novel GABAB antagonist CGP 35348.
Inhibition of central monoamine oxidase by imidazoline2 site-selective ligands.
Initial evaluation of novel selective ligands for imidazoline(2) receptors in rat whole brain.
Integrating the cognitive and physiological aspects of craving
Interactions of the imidazodiazepine Ro 15-4513 with chemical convulsants.
International consensus statement on major depressive disorder.
Introduction. The neurobiology of drug addiction: new vistas.
Investigating benzodiazepine receptor function in vivo using an intravenous infusion of DMCM.
Investigation of the affinities of two new beta-carbolines for rat brain imidazoline(2) receptors.
Investigation of the different types of opioid receptor involved in electroconvulsive shock-induced antinociception and catalepsy in the rat.
Investigation of the involvement of opioid receptors in the action of anticonvulsants.
Investigation of the sleep electrocorticogram of the common marmoset (Callithrix jacchus) using radiotelemetry.
Investigations on the "set-point" theory of benzodiazepine receptor function.
Invited review: the evolution of antidepressant mechanisms.
Is the association of hypertension and panic disorder explained by clustering of autonomic panic symptoms in hypertensive patients?
IS THERE COGNITIVE IMPAIRMENT IN CLINICALLY 'HEALTHY' ABSTINENT ALCOHOL DEPENDENCE?
Isolation of RP-HPLC pure clonidine-displacing substance from NG108-15 cells.
Kennedy, Sidney H. ... [et al.]: Treating depression effectively : applying clinical guidelines, c2007
Lactate and hyperventilation substantially attenuate vagal tone in normal volunteers. A possible mechanism of panic provocation?
Lactate-induced electrolyte changes in the cerebrospinal fluid of rabbits.
Lithium treatment effect on serotonin function.
Long-term treatment strategies in anxiety disorders.
Loss of consciousness and post-traumatic stress disorder. A clue to aetiology and treatment.
Low affinity hypothalamic [3H]mazindol binding: a probe for hypothalamic body weight regulation?
Low sensitivity of the positron emission tomography ligand [11C]diprenorphine to agonist opiates.
Maintenance buprenorphine for opioid users
Making sense of GABA(A) receptor subtypes: is a new nomenclature needed?
Making sense of GABA~A receptor subtypes : is a new nomenclature needed?
Management of insomnia: treatments and mechanisms
Management of insomnia: treatments and mechanismsi.
Management of patients with depression associated with anxiety symptoms.
Manifesto for a European anxiety disorders research network.
MDMA, politics and medical research: Have we thrown the baby out with the bathwater?
Measuring endogenous 5-HT release by emission tomography: promises and pitfalls.
Mechanism of action of antidepressants.
Mechanisms of action of selective serotonin reuptake inhibitors in the treatment of psychiatric disorders.
Mice and rats are sensitized to the proconvulsant action of a benzodiazepine-receptor inverse agonist (FG 7142) following a single dose of lorazepam.
Microbial infections in eight genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis.
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
Mirtazapine: pharmacology in relation to adverse effects.
Monoamine oxidase inhibitors: rehabilitation from recent research?
Mood and anxiety disorders in children and adolescents : a psychopharmacological approach
Mourning and melancholia revisited: correspondences between principles of Freudian metapsychology and empirical findings in neuropsychiatry.
N1'-fluoroethyl-naltrindole (BU97001) and N1'-fluoroethyl-(14-formylamino)-naltrindole (BU97018) potential delta-opioid receptor PET ligands.
Naloxone displacement at opioid receptor sites measured in vivo in the human brain.
National Institute of Drug Abuse Research Monograph Series: Assessing Neurotoxicity of Drugs of Abuse
Neurobiological mechanisms in generalized anxiety disorder.
Neurobiology of addiction and implications for treatment.
Neurobiology of addiction, The : new vistas
Neuroendocrine and clinical effects of electroconvulsive therapy and their relationship to treatment outcome.
Neuropharmacological and clinical aspects of alcohol withdrawal.
neuropharmacology of serotonin and noradrenaline in depression., The
New approaches to drug dependency
new human (psycho)pharmacology tool: the multiple organs coincidences counter (MOCC), A
New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder.
NHS drug budget. Flawed assumption in analysis.
NICE : The National Institute of Clinical Excellence - or Eccentricity? Reflections on the Z-drugs as hypnotics
NIH conference. Alcohol withdrawal and noradrenergic function.
non-inferiority comparison of duloxetine and venlafaxine in the treatment of adult patients with generalized anxiety disorder, A
Noradrenaline in depression: half a century of progress.
Noradrenergic function in generalized anxiety disorder: impact of treatment with venlafaxine on the physiological and psychological responses to clonidine challenge
Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality.
Noradrenergic mechanisms in the prefrontal cortex.
Not only but also? Comments on "How does convulsive therapy work"?
Novel ligands for the investigation of imidazoline receptors and their binding proteins.
Novel selective compounds for the investigation of imidazoline receptors.
On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain.
On the measurement in rats of the convulsant effect of drugs and the changes which follow electroconvulsive shock.
[On the role of GABA in anxiety and depression].
Optimizing the pentetrazol infusion test for seizure threshold measurement.
Orexin-A Infusion in the Locus Ceruleus Triggers Norepinephrine (NE) Release and NE-Induced Long-Term Potentiation in the Dentate Gyrus
Organization of Opioid Receptors in Human Brain and Drug Interactions Studied by PET and SPECT Imaging: Implications for Treatment Strategies for Opiate Addiction
other face of depression, reduced positive affect: the role of catecholamines in causation and cure., The
Overexcitement and disinhibition. Dynamic neurotransmitter interactions in alcohol withdrawal.
Overview of diagnosis and drug treatments of anxiety disorders.
Panic and hypertension: brothers in arms through 5-HT?
Panic attacks. A neurochemical overview of models and mechanisms.
Panic attacks and alcohol withdrawal: can subjects differentiate the symptoms?
Panic disorder : Clinical diagnosis, management and mechanisms
Panic response to lactate administration in alcoholic and nonalcoholic patients with panic disorder.
Panikku shōgai : Byōtai kara chiryō made
Papel de la noradrenalina y la dopamina en su patología y tratamiento, El : simposio satélite : Viena, 16 de octubre de 2007
Performance effects of diazepam during and after prolonged administration.
pharmacodynamic study of the alpha 2-adrenergic receptor antagonist ethoxyidazoxan in healthy volunteers., A
Pharmacological and behavioural studies of benzodiazepine antagonists and contragonists.
Pharmacological characterisation of novel alpha sub(2)-adrenoceptor antagonists as potential brain imaging agents
Pharmacology of saccadic eye movements in man. 1. Effects of the benzodiazepine receptor ligands midazolam and flumazenil.
Pharmacology of saccadic eye movements in man. 2. Effects of the alpha 2-adrenoceptor ligands idazoxan and clonidine.
physical health challenges in patients with severe mental illness: cardiovascular and metabolic risks, The
pilot controlled study of the effects of flumazenil in posttraumatic stress disorder., A
pilot study of the effectiveness of D-cycloserine during cue-exposure therapy in abstinent alcohol-dependent subjects., A
pilot study on the effects of treatment with acamprosate on craving for alcohol in alcohol-dependent patients., A
Pindolol augmentation of sertraline in resistant depression and its effect on sleep
Platelet alpha 2-adrenoceptor binding does not predict brain alpha 2-adrenoceptor function.
Platelet binding studies in panic disorder.
Platelet monamine receptor binding in alcoholics during withdrawal.
Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial.
Potential Novel Anxiolytic Drugs
Potentiation of barbiturate-induced alterations in presynaptic noradrenergic function in rat frontal cortex by imidazol(in)e alpha2-adrenoceptor agonists.
Preparation, structure and affinity for imidazoline I2 receptors and alpha2-adrenoceptors of 1-[(4,5-dihydroimidazolidin-2-yl)imino]indan-2-ols.
Prescribing antidepressants post Cipriani et al.
Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand.
processing of automatic thoughts of drug use and craving in opiate-dependent individuals., The
proof-of-concept study using [11C]flumazenil PET to demonstrate that pagoclone is a partial agonist, A
psychobiology of anxiolytic drug. Part 2: Pharmacological treatments of anxiety., The
psychobiology of anxiolytic drugs. Part 1: Basic neurobiology., The
psychobiology of posttraumatic stress disorder., The
psychopharmacological treatment algorithm for generalised anxiety disorder (GAD)., A
Psychotropic drugs, cardiac arrhythmia, and sudden death.
Putting the `A' in atypical : does α~2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics?
Putting the 'A' in atypical: does alpha 2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics?
Quantification of in vivo binding of [3H]RX 821002 in rat brain: evaluation as a radioligand for central alpha 2-adrenoceptors.
"'Tis a wonder it works at all!"
Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites--current status.
Randomised controlled study of sleep after nefazodone or paroxetine treatment in out-patients with depression.
Rapid induction of lorazepam dependence and reversal with flumazenil.
Rapid tryptophan depletion following cognitive behavioural therapy for panic disorder.
Rationale for, barriers to, and appropriate medication for the long-term treatment of depression.
Redistribution of slow wave activity of sleep during pharmacological treatment of depression with paroxetine but not with nefazodone.
Reduced thalamic grey matter volume in opioid dependence is influenced by degree of alcohol use: a voxel-based morphometry study
Regional GABA concentration and [3H]-diazepam binding in rat brain following repeated electroconvulsive shock.
Regional neurotransmitter responses after acute and chronic electroconvulsive shock.
Regionally specific changes in extracellular noradrenaline following chronic idazoxan as revealed by in vivo microdialysis.
Relationship between imidazoline(2) sites and monoamine oxidase.
Relationship of neurotransmitters to the symptoms of major depressive disorder.
Repeated administration of subconvulsant doses of GABA antagonist drugs. I. Effect on seizure threshold (kindling).
Repeated administration of subconvulsant doses of GABA antagonist drugs. II. Effect on monoamine-mediated behaviour.
Repeated electroconvulsive shock does not change [3H]-paroxetine binding to the 5-HT uptake site in rat cortical membranes.
Repeated electroconvulsive shock does not increase the susceptibility of rats to a cage convulsant (isopropylbicyclophosphate).
Repeated electroconvulsive shock increases the number of [3H]desipramine binding sites in rat cerebral cortex.
Repeated electroconvulsive shock normalizes blood glucose levels in genetically obese mice (C57BL/6J ob/ob) but not in genetically diabetic mice (C57BL/KsJ db/db).
Reply from the editor.
Reply to letter by Green, Marsden and Fone (2007) about Sessa and Nutt's editorial (MDMA: baby with the bath water) in the November 2007 Journal
Resolution of Sleepiness and Fatigue in Major Depressive Disorder: A Comparison of Bupropion and the Selective Serotonin Reuptake Inhibitors
RO 15-4513 and its interaction with ethanol.
RO 15-4513 does not protect rats against the lethal effects of ethanol.
role of central noradrenergic dysregulation in anxiety disorders: evidence from clinical studies, The
role of dopamine and norepinephrine in depression and antidepressant treatment., The
Role of GABA in anxiety and depression
Saccadic eye movement parameters in normal subjects.
Science and non-science in UK drug policy.
Searching for perfect sleep: the continuing evolution of GABAA receptor modulators as hypnotics.
Sedative antidepressants impair visual detection mechanisms in humans
'Seeing through a glass darkly': casting light on imidazoline 'I' sites.
Selective changes in the in vivo effects of benzodiazepine receptor ligands after chemical kindling with FG 7142.
Selective delta-opioid receptor ligands: potential PET ligands based on naltrindole.
Selective effect of lithium on cognitive performance in man.
Selective serotonin reuptake inhibitors: meta-analysis of discontinuation rates.
Septal driving of hippocampal theta rhythm: role of gamma-aminobutyrate-benzodiazepine receptor complex in mediating effects of anxiolytics.
Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study
Serotonin and Sensitivity to Trauma-Related Exposure in Selective Serotonin Reuptake Inhibitors- Recovered Posttraumatic Stress Disorder
Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression
Sertraline, a selective serotonin reuptake inhibitor modulates extracellular noradrenaline in the rat frontal cortex
Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes
Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge
single dose of FG 7142 causes long-term increases in mouse cortical beta-adrenoceptors., A
single electroconvulsive shock substantially lowers blood glucose levels in obese mice (C57BL/6J ob/ob)., A
single preexposure produces sensitization to the locomotor effects of cocaine in mice., A
Sleep and daytime sleepiness the next day following single night-time dose of fluvoxamine, dothiepin and placebo in normal volunteers.
Sleep changes during long-term treatment of depression with fluvoxamine--a home-based study.
Sleep disorders as core symptoms of depression.
Some important changes.
Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder.
Strain differences in response to a benzodiazepine receptor inverse agonist (FG 7142) in mice.
Strain differences in sensitivity to the hypothermic effects of benzodiazepine receptor ligands in mice.
Structural and functional brain changes in posttraumatic stress disorder.
Studies of alpha-2-adrenoceptor function in abstinent alcoholics.
Studies on [3H]diazepam and [3H]ethyl-beta-carboline carboxylate binding to rat brain in vivo. I. Regional variations in displacement.
Studies on [3H]diazepam and [3H]ethyl-beta-carboline carboxylate binding to rat brain in vivo. II. Effects of electroconvulsive shock.
Studies on the post-ictal rise in seizure threshold.
Substance-P antagonists : a new treatment for depression?
Substance P antagonists: novel agents in the treatment of depression
Successful treatment of fluvoxamine-induced anorgasmia by cyproheptadine.
Successful treatment of night terrors and somnambulism with paroxetine.
Synthesis of 2,3,5,6-tetrahydro-3H-imidazo[2,1-b] [1,3,5]benzotriazepines and their oxidative ring contraction into 1-(4,5-dihydro-1H-imidazol-2-yl)-1H-benzimidazoles.
tale of two Es, A
technique for chronic catheterization of the cisterna magna in rabbits., A
That warm fuzzy feeling: brain serotonergic neurons and the regulation of emotion.
Thyroid hormones do not alter rat brain benzodiazepine receptor function in-vivo.
Thyrotropin-releasing hormone: a potential comparator for the panicogenic effects of pentagastrin and CCK?
Thyrotropin-releasing hormone selectively reverses lorazepam-induced sedation but not slowing of saccadic eye movements.
TNF alpha mimics the endocrine but not the thermoregulatory responses of bacterial lipopolysaccharide (LPS): correlation with FOS-expression in the brain.
Tolerability and safety aspects of mirtazapine.
translational, caffeine-induced model of onset insomnia in rats and healthy volunteers, A
Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function.
Trastornos del sueño
Treatment of anxiety and depressive disorders in patients with cardiovascular disease
Tryptophan depletion and its implications for psychiatry.
Tryptophan depletion does not modify response to CCK-4 challenge in patients with panic disorder after treatment with citalopram
Tryptophan depletion reverses the therapeutic effect of selective serotonin reuptake inhibitors in social anxiety disorder.
Tryptophan metabolism in the central nervous system: medical implications
Uncritical positive regard? Issues in the efficacy and safety of psychotherapy
Understanding the neurobiology of comorbidity in anxiety disorders.
unhappy saga of `happy pills', The
unhappy saga of 'happy pills', The
Unusual interactions of benzodiazepine receptor antagonists.
Update on Posttraumatic Stress Disorder
uptake of a fluorescently labelled antisense oligonucleotide in vitro and in vivo., The
use of benzodiazepines in anxiety and other disorders., The
Use of selective serotonin reuptake inhibitors and other serotonergic drugs in the biological dissection of affective disorders.
use of sleep measures to compare a new 5HT1A agonist with buspirone in humans, The
User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study
Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: clinical and preclinical studies.
Using Ro 15-1788 to investigate the benzodiazepine receptor in vivo: studies on the anticonvulsant and sedative effect of melatonin and the convulsant effect of the benzodiazepine Ro 05-3663.
Using saccadic eye movements as objective measures of tolerance in methadone dependent individuals during the hydromorphone challenge test.
Using sleep to evaluate comparative serotonergic effects of paroxetine and citalopram.
validation of the 7.5% CO sub(2) model of GAD using paroxetine and lorazepam in healthy volunteers, A
validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers, A
Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain.
Venlafaxine: a new class of antidepressant.
Venlafaxine occupation at the noradrenaline reuptake site: in-vivo determination in healthy volunteers
Vienna Declaration: a call for evidence-based drug policies.
Voluntary exercise alters GABA(A) receptor subunit and glutamic acid decarboxylase-67 gene expression in the rat forebrain.
WCA recommendations for the long-term treatment of generalized anxiety disorder.
WCA recommendations for the long-term treatment of obsessive-compulsive disorder in adults.
WCA recommendations for the long-term treatment of panic disorder.
WCA Recommendations for the long-term treatment of posttraumatic stress disorder.
WCA recommendations for the long-term treatment of social phobia.
What one hand giveth the other taketh away: some unpredicted effects of enantiomers in psychopharmacology
Which antidepressants have demonstrated superior efficacy? A review of the evidence.
Why does the world have such a 'down' on antidepressants?
Wine and drug evaluations: lessons on making comparisons of noninferiority
Women with diarrhoea-predominant irritable bowel syndrome show an increased pressure response to 35% carbon dioxide stress challenge.
パニック障害 : 病態から治療まで
Contributed to or performed:
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
JOURNAL OF CLINICAL PSYCHIATRY
JOURNAL OF PSYCHOPHARMACOLOGY -OXFORD-
Thesis--Oxford University 1983