|results||search [or]||| 1 hits|
0000 0001 2032 7658
Fred Gage (American geneticist)
Fred Gage (Amerikaans klinische genetica)
Fred H. Gage (US-amerikanischer Neurobiologe)
Fred Harrison Gage
Gage, F. H.
Gage, Fred H.
American Academy of Arts and Sciences
Arthur M. Sackler Colloquia of the National Academy of Sciences (2002 : Irvine, Calif.)
Björklund, Anders (1945-....))
Christen, Yves (1948-...)
Christen, Yves (1948-..)
Cold Spring Harbor Laboratory
Johns Hopkins University
Prochiantz, Alain (1948-....))
Verma, Inder M.
10-amino acid sequence of fibroblast growth factor 2 is sufficient for its mitogenic activity on neural progenitor cells, A
Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice.
Absence of long-term potentiation in the subcortically deafferented dentate gyrus.
Acetylcholine-secreting cells improve age-induced memory deficits.
Adeno-associated virus effectively mediates conditional gene modification in the brain.
Adrenal chromaffin cells as multipotential neurons for autografts.
Adrenal chromaffin cells transdifferentiate in response to basic fibroblast growth factor and show directed outgrowth to a nerve growth factor source in vivo.
Adult-Generated Neurons in the Dentate Gyrus Send Axonal Projections to Field CA sub(3) and Are Surrounded by Synaptic Vesicles
Adult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles.
Adult neurogenesis: integrating theories and separating functions.
adult rat hippocampus contains primordial neural stem cells., The
adult substantia nigra contains progenitor cells with neurogenic potential., The
Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy
Age-related impairments in spatial memory are independent of those in sensorimotor skills.
Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats.
Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice
Alternative splicing events identified in human embryonic stem cells and neural progenitors.
Alzheimer's disease and spirochetes; a questionable relationship.
Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome.
Application of ex vivo gene therapy in the treatment of Parkinson's disease.
Applications of gene therapy to the CNS.
Are somatic stem cells pluripotent or lineage-restricted?
Astrocytes are important for sprouting in the septohippocampal circuit.
Astroglia induce neurogenesis from adult neural stem cells.
Astroglia induced neurogenesis from adult neural stem cells
Autocrine differentiation of PC12 cells mediated by retroviral vectors.
Axonal regeneration and limited functional recovery following hippocampal deafferentation.
Basal forebrain cell loss following fimbria/fornix transection.
Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75
Basic FGF-SAP mitotoxin in the hippocampus. Specific lethal effect on cells expressing the basic FGF receptor.
Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease
Bcl-xL protects adult septal cholinergic neurons from axotomized cell death
Bipotent progenitor cell lines from the human CNS.
Brain-derived neurotrophic factor-transduced fibroblasts: Production of BDNF and effects of grafting to the adult rat brain
Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery.
Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines.
Can stem cells cross lineage boundaries?
Cdk5 Regulates Accurate Maturation of Newborn Granule Cells in the Adult Hippocampus
Cell culture: Progenitor cells from human brain after death
Cell fusion causes confusion
Cell fusion-independent differentiation of neural stem cells to the endothelial lineage
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells.
Cells engineered to produce acetylcholine: therapeutic potential for Alzheimer's disease.
Cellular activity of intracerebrally transplanted fetal hippocampus during behavior.
Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.
Cellular Interactions in the Stem Cell Niche
Cellular replacement therapy for neurologic disorders: potential of genetically engineered cells.
Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75.
Changes in protein kinase C isozymes in the rat hippocampal formation following hippocampal lesion.
Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency.
Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits.
cholinergic nucleus basalis: a key structure in neocortical arousal., The
Cholinergic sprouting in the hippocampus: a proposed role for IL-1.
Cholinergic strategies for Alzheimer's disease.
Chromatin remodeling in neural development and plasticity
Chronic Neurotrophin-3 Strengthens Synaptic Connections to Motoneurons in the Neonatal Rat
Closer to neurogenesis in adult humans
Comparison of substance K-like and substance P-like fibers and cells in the rat hippocampus.
Computational Influence of Adult Neurogenesis on Memory Encoding
conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain., A
Conference on Stem Cells: Origins, Fate and Functions
Constitutive retinoid receptors expressed from adenovirus vectors that specifically activate chromosomal target genes required for differentiation of promyelocytic leukemia and teratocarcinoma cells.
Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines.
Cytokine regulation of nerve growth factor-mediated cholinergic neurotrophic activity synthesized by astrocytes and fibroblasts.
Defining the NG2-expressing cell of the adult CNS.
Delayed treatment with nerve growth factor improves acquisition of a spatial task in rats with lesions of the nucleus basalis magnocellularis: evaluation of the involvement of different neurotransmitter systems.
Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo
Dentate Gyrus-Specific Knockdown of Adult Neurogenesis Impairs Spatial and Object Recognition Memory in Adult Rats
Development of a novel mouse glioma model using lentiviral vectors
Development of a self-inactivating lentivirus vector
Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors.
Development of functional human embryonic stem cell-derived neurons in mouse brain
Development of neural circuits in the adult hippocampus.
Development of the basal forebrain cholinergic system: phenotype expression prior to target innervation.
Differential expression of protein kinase C isozymes in rat cerebellum.
Differential expression of protein kinase C isozymes in rat glial cell cultures.
Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo
Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene
Directed differentiation of hippocampal stem/progenitor cells in the adult brain
Disease, transplantation and regeneration.
Distinct Morphological Stages of Dentate Granule Neuron Maturation in the Adult Mouse Hippocampus
distinctive layering pattern of mouse dentate granule cells is generated by developmental and adult neurogenesis., A
DNA repair proteins affect the lifecycle of herpes simplex virus 1
Dopaminergic cells align along radial glia in the developing mesencephalon of the rat.
Dopaminergic modulation of cortical inputs during maturation of adult-born dentate granule cells.
Downregulation of muscarinic receptors in the rat caudate-putamen after lesioning of the ipsilateral nigrostriatal dopamine pathway with 6-hydroxydopamine (6-OHDA): normalization by fetal mesencephalic transplants.
Effects of brain-derived neurotrophic factor and nerve growth factor on remaining neurons in the lesioned nucleus basalis magnocellularis.
Effects of choline and quiescence on Drosophila choline acetyltransferase expression and acetylcholine production by transduced rat fibroblasts.
Effects of confinement, previous experience and hippocampal damage on the DRL schedule.
Effects of gene transfer into cultured CNS neurons with a replication-defective herpes simplex virus type 1 vector.
Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male sprague-dawley rats in vivo
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
Electric activity in the neocortex of freely moving young and aged rats.
Electrophysiological characteristics of cells within mesencephalon suspension grafts.
Embryonic stem cells: staying plastic on plastic
Employment of fibroblasts for gene transfer: applications for grafting into the central nervous system.
Endogenous FGF-2 is important for cholinergic sprouting in the denervated hippocampus.
Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury.
Enhanced survival and neuronal differentiation of adrenal chromaffin cells cografted into the striatum with NGF-producing fibroblasts
Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis.
Environmental influence on L1 retrotransposons in the adult hippocampus.
Environmental stimulation of 129/SvJ mice causes increased cell proliferation and neurogenesis in the adult dentate gyrus.
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain.
Epigenetic choreographers of neurogenesis in the adult mammalian brain.
Epigenetic control of neural stem cell fate.
[Epigenetic mechanisms regulating neural cell fate determination].
Epigenetic Modulation of Seizure-Induced Neurogenesis and Cognitive Decline
Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain
Epigenetic Regulation of the Stem Cell Mitogen Fgf-2 by Mbd1 in Adult Neural Stem/Progenitor Cells.
Essential role of neocortical acetylcholine in spatial memory
Estradiol enhances neurogenesis following ischemic e through estrogen receptors alpha and beta
Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta.
Ex vivo and in vivo gene delivery to the brain.
Exercise Enhances Learning and Hippocampal Neurogenesis in Aged Mice
Experience-Induced Neurogenesis in the Senescent Dentate Gyrus
Experimental approaches to age-related cognitive impairments.
Expression and function of orphan nuclear receptor TLX in adult neural stem cells.
Expression of biologically active basic fibroblast growth factor by genetically modified rat primary skin fibroblasts
Expression of L1 and PSA during sprouting and regeneration in the adult hippocampal formation
Extracellular properties of cells within mesencephalon suspension grafts in rat striatum.
Factors affecting proviral expression in primary cells grafted into the CNS.
Fate of endogenous stem/progenitor cells following spinal cord injury
FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord.
FGF-2-Responsive Neural Stem Cell Proliferation Requires CCg, a Novel Autocrine/Paracrine Cofactor
FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain.
Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS.
Fibroblast growth factor-2-producing fibroblasts protect the nigrostriatal dopaminergic system from 6-hydroxydopamine
Fibroblast growth factor-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death
Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes.
FUNCTIONAL AND ANATOMICAL ANALYSIS OF REGENERATION IN THE CNS
Functional and morphological effects of NG2 proteoglycan deletion on hippocampal neurogenesis.
Functional convergence of neurons generated in the developing and adult hippocampus.
Functional neurogenesis in the adult hippocampus.
Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra.
Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation., A
functional study of miR-124 in the developing neural tube, A
GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus.
Gene therapy for neurologic disease.
Gene therapy in the adult primate brain: Intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration
Gene therapy in the CNS: intracerebral grafting of genetically modified cells.
Gene transfer and therapy in the nervous system
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis
Gene transfer into established and primary fibroblast cell lines: comparison of transfection methods and promoters.
Gene transfer to the rodent placenta in situ. A new strategy for delivering gene products to the fetus.
Generation and Analysis of GluR5(Q636R) Kainate Receptor Mutant Mice
Generation and culturing of precursor cells and neuroblasts from embryonic and adult central nervous system.
Generation of neuronal variability and complexity
Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells.
Genetic influence on neurogenesis in the dentate gyrus of adult mice
Genetic influence on phenotypic differentiation in adult hippocampal neurogenesis
Genetically modified cells: applications for intracerebral grafting.
Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource.
grafted hippocampus: an epileptic focus., The
Grafting genetically modified cells to the brain: conceptual and technical issues.
Grafting genetically modified cells to the brain: possibilities for the future.
Grafting in the mammalian central nervous system
Grafting of nerve growth factor-producing fibroblasts reduces behavioral deficits in rats with lesions of the nucleus basalis magnocellularis.
Grafts of fetal cholinergic neurons to the deafferented hippocampus.
Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord.
High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor.
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector
Hippocampal grafts into the intact brain induce epileptic patterns.
Hippocampal grafts of acetylcholine-producing cells are sufficient to improve behavioural performance following a unilateral fimbria-fornix lesion
Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice.
Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
Hormone receptor functional dimers and methods of their use
Human amnion membrane matrix as a substratum for axonal regeneration in the central nervous system.
Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice
Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation.
Identification of small molecules from human embryonic stem cells using metabolomics.
Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression.
IGF-I has a direct proliferative effect in adult hippocampal progenitor cells
IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes.
In vivo assay of neuron-specific effects of nerve growth factor.
In vivo demonstration that a-synuclein oligomers are toxic
In vivo demonstration that alpha-synuclein oligomers are toxic.
In vivo Evidence for Radial Migration of Neurons by Long-Distance Somal Translocation in the Developing Ferret Visual Cortex
In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus.
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
In vivo production and release of acetylcholine from primary fibroblasts genetically modified to express choline acetyltransferase.
Intracerebral delivery of growth factors: potential application of genetically modified fibroblasts.
Intracerebral grafting: A tool for the neurobiologist.
Intracerebral grafting in the dopaminergic system: issues and controversy.
Intracerebral grafting of cultured autologous skin fibroblasts into the rat striatum: an assessment of graft size and ultrastructure.
Intracerebral grafting of genetically modified cells acting as biological pumps.
Intracerebral grafting of genetically modified cells. Applications to a rat model of Parkinson's disease.
Intracerebral transplantation: basic and clinical applications to the neostriatum.
Intracerebral xenografts: Sertoli cells to the rescue?
Intraneuronal aggregate formation and cell death after viral expression of expanded polyglutamine tracts in the adult rat brain.
Investigating synapse formation and function using human pluripotent stem cell-derived neurons
Isolation, characterization, and use of stem cells from the CNS.
Isolation, characterization, and utilization of CNS stem cells
L1 retrotransposition in human neural progenitor cells
L1 retrotransposition in neurons is modulated by MeCP2.
LINE-1 retrotransposition in human embryonic stem cells
LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?
Localization of hypoxanthine-guanine phosphoribosyltransferase mRNA in the mouse brain by in situ hybridization.
Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice.
Long-term potentiation of evoked and spontaneous neuronal activity in the grafted hippocampus.
Long-term production of choline acetyltransferase in the CNS after transplantation of fibroblasts modified with a regulatable vector.
Maintaining the neuronal phenotype after injury in the adult CNS. Neurotrophic factors, axonal growth substrates, and gene therapy.
Mammalian neural stem cells.
Mechanisms and functional implications of adult neurogenesis.
Mechanisms of sprouting in the adult central nervous system: cellular responses in areas of terminal degeneration and reinnervation in the rat hippocampus.
Mechanisms Underlying Inflammation in Neurodegeneration
Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons
Method for increasing cognitive function and neurogenesis
Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system
Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system.
Method of isolating adult mammalian CNS-derived progenitor stem cells using density gradient centrifugation
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function.
miR-9 and TLX: chasing tails in neural stem cells
Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells, A
Modelling schizophrenia using human induced pluripotent stem cells.
Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus.
More hippocampal neurons in adult mice living in an enriched environment.
Morphologic alterations of choline acetyltransferase-positive neurons in the basal forebrain of aged behaviorally characterized Fisher 344 rats.
Morphological and neurochemical features of cultured primary skin fibroblasts of Fischer 344 rats following striatal implantation.
Morphological response of axotomized septal neurons to nerve growth factor.
Mouse model of neurodegeneration: atrophy of basal forebrain cholinergic neurons in trisomy 16 transplants.
Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells.
Multipotent progenitor cells in the adult dentate gyrus.
Multisite recording of brain field potentials and unit activity in freely moving rats.
multivariate analysis of social dominance in rats, A
Nat. fac. dir. '89
Natural variation and genetic covariance in adult hippocampal neurogenesis
necessary junk: new functions for transposable elements., The
Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice
Neprilysin protects neurons against A beta peptide toxicity
Neprilysin protects neurons against Abeta peptide toxicity.
Neprilysin regulates amyloid Beta peptide levels.
Nerve growth factor function in the central nervous system.
Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration.
Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection.
Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments.
Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: response to fimbria-fornix transection.
Nerve growth factor receptor immunoreactivity in the rat septohippocampal pathway: a light and electron microscope investigation.
Neural consequences of environmental enrichment
Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons.
Neural transplants: prospects for Alzheimer's disease.
Neurobiology of disease.
Neurogenesis : a subject collection from Cold Spring Harbor Perspectives in Biology
Neurogenesis and neuroadaptation.
Neurogenesis in the adult brain: new strategies for central nervous system diseases.
Neurogenesis in the adult hippocampus.
Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
Neuronal activity in the subcortically denervated hippocampus: a chronic model for epilepsy.
Neuronal grafting and Alzheimer's disease [proceedings of the 3rd Colloque Médecine et recherche, held in September 1988 in Montpellier]
NEURONAL PRECURSOR CELLS FOR TRANSPLANT AFTER CNS TRAUMA
NEURONAL PRECURSOR CELLS FOR TRANSPLANTATION AFTER CNS
Neuronal stem cells: their characterization and utilization.
Neurons born in the adult dentate gyrus form functional synapses with target cells
Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease.
Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis.
Neuroscience. Cellular interactions in the stem cell niche.
Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism.
Neurotrophic factors and diseases of the nervous system.
neurotrophic hypothesis and the cholinergic basal forebrain projection., The
Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
[New nerve cells for the adult brain. Adult neurogenesis and stem cell concepts in neurologic research].
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
New regulators in adult neurogenesis and their potential role for repair.
NGF-dependent sprouting and regeneration in the hippocampus.
NGF improves spatial memory in aged rodents as a function of age.
NGF increases cortical acetylcholine release in rats with lesions of the nucleus basalis.
NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat.
NGF receptor reexpression and NGF-mediated cholinergic neuronal hypertrophy in the damaged adult neostriatum.
Nicotinic Receptor-Induced Apoptotic Cell Death of Hippocampal Progenitor Cells
NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus
Non-Cell-Autonomous Effect of Human SOD1 super(G37R) Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
Noncoding RNAs in the mammalian central nervous system.
Normalization of subtype-specific muscarinic receptor binding in the denervated hippocampus by septodiagonal band grafts.
Notch keeps ependymal cells in line.
novel model for an older remodeler: the BAF swap in neurogenesis., A
Novel neuronal phenotypes from neural progenitor cells.
Novel therapeutic directions for Parkinson's disease.
NRSE smRNA specifies the fate of adult hippocampal neural stem cells., The
Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1
Nucleus basalis and thalamic control of neocortical activity in the freely moving rat.
Nucleus basalis lesions fail to induce senile plaques in the rat.
Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain
Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death, A
Orphan nuclear receptor TLX activates Wnt/ beta -catenin signalling to stimulate neural stem cell proliferation and self-renewal
Packaging Cell Line for Lentivirus Vectors, A
Parkinson's disease. Fetal implants put to the test.
Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior.
Perforant path damage results in progressive neuronal death and somal atrophy in layer II of entorhinal cortex and functional impairment with increasing postdamage age.
Plant-Derived Flavanol (-)Epicatechin Enhances Angiogenesis and Retention of Spatial Memory in Mice
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases.
Potential effect of cytokines on transgene expression in primary fibroblasts implanted into the rat brain
Potential role for adult neurogenesis in the encoding of time in new memories
Potential use of nerve growth factor to treat Alzheimer's disease.
Potential use of neurotrophic agents in the treatment of neurodegenerative disorders.
Programmed Cells from Basic Neuroscience to Therapy
Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging.
Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord.
Proliferation, differentiation, and long-term culture of primary hippocampal neurons.
Put them out to pasture? What are old granule cells good for, anyway...?
Quantitative effects of cerebral infarction on spatial learning in rats.
Radical directions in Parkinson's disease.
Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor.
Reactive astrocytes: cellular and molecular cues to biological function.
Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat.
Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain.
Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction
Regenerating the damaged central nervous system
Regeneration in the adult and aging brain
Regeneration in the adult mammalian CNS: guided by development.
Regulatable acetylcholine-producing fibroblasts enhance cognitive performance.
Regulatable retrovirus system for genetic modification of cells
Regulation of voltage- and ligand-gated currents in rat hippocampal progenitor cells in vitro
Repression of Human Fibroblast Growth Factor 2 by a Novel Transcription Factor
Rescue from Photoreceptor Degeneration in the rd Mouse by Human Immunodeficiency Virus Vector-Mediated Gene Transfer
Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation.
Restoration of function to the denervated spinal cord after implantation of embryonic 5HT- and substance P-containing raphe neurones.
Retinoic Acid and Neurotrophins Collaborate to Regulate Neurogenesis in Adult-Derived Neural Stem Cell Cultures
Retinoic acid is required early during adult neurogenesis in the dentate gyrus
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
Retrotransposition, diversity, and the brain
Retrovirus-mediated expression of an artificial beta-endorphin precursor in primary fibroblasts.
Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo.
Reversal of nigrostriatal-lesion-induced receptor alterations by grafting of fetal mesencephalic dopaminergic neurons.
Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor.
RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells, An
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors
role for adult TLX-positive neural stem cells in learning and behaviour, A
role for bone marrow-derived cells in the vasculature of noninjured CNS., A
Running enhances neurogenesis, learning, and long-term potentiation in mice.
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
search for neural progenitor cells: prospects for the therapy of neurodegenerative disease., The
Seizure-Associated, Aberrant Neurogenesis in Adult Rats Characterized with Retrovirus-Mediated Cell Labeling
Signaling in adult neurogenesis.
Signaling through BMPR-IA Regulates Quiescence and Long-Term Activity of Neural Stem Cells in the Adult Hippocampus
Similar GABAergic inputs in dentate granule cells born during embryonic and adult neurogenesis
Small Gem with Great Powers: Geminin Keeps Neural Progenitors Thriving, A
small modulatory dsRNA specifies the fate of adult neural stem cells., A
Somatic gene therapy for nervous system disease.
Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats.
Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration.
Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
Spinal cord neuroblasts proliferate in response to basic fibroblast growth factor
Spontaneous Fusion and Nonclonal Growth of Adult Neural Stem Cells
Sprouting adult CNS cholinergic axons express NILE and associate with astrocytic surfaces expressing neural cell adhesion molecule.
Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector
Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations.
Stem cell technology for basic science and clinical applications
Stem cells in the nervous system functional and clinical implications
Stem cells of the central nervous system.
Stem cells: the good, bad and barely in control
Storage, metabolism, and processing of 125I-fibroblast growth factor-2 after intracerebral injection.
Suppression and induction of epileptic activity by neuronal grafts.
Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain
Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-dopa.
Survival, growth and function of damaged cholinergic neurons.
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors.
Synapse formation on neurons born in the adult hippocampus
Synaptic loss in cognitively impaired aged rats is ameliorated by chronic human nerve growth factor infusion
Synergy of insulin-like growth factor-1 and exercise in amyotrophic lateral sclerosis
synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells., A
Targeted expression of IGF-1 in the central nervous system fails to protect mice from experimental autoimmune encephalomyelitis
Targeted retrograde gene delivery for neuronal protection.
Targeted retrograde gene delivery to motor neurons
Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model
Therapeutic interventions after spinal cord injury
Therapeutic interventions for spinal cord injury
THERAPEUTIC POTENTIALS OF CNS STEM CELLS
Thymidine kinase-mediated killing of rat brain tumors.
Transcriptional Profiling Reveals Strict Boundaries Between Hippocampal Subregions
Transcriptional signature and memory retention of human-induced pluripotent stem cells.
TrkA activation is sufficient to rescue axotomized cholinergic neurons
Trophic regulation of basal forebrain gene expression in aging and Alzheimer's disease.
Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations.
Unconventional translation of mammalian LINE-1 retrotransposons.
Vascular niche for adult hippocampal neurogenesis.
Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis
What is the brain good for?
Widespread Integration and Survival of Adult-Derived Neural Progenitor Cells in the Developing Optic Retina
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis
Wnt signalling regulates adult hippocampal neurogenesis
YAP regulates neural progenitor cell number via the TEA domain transcription factor
Contributed to or performed:
CURRENT OPINION IN NEUROBIOLOGY
CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY
GENES AND DEVELOPMENT
JOURNAL OF COMPARATIVE NEUROLOGY
JOURNAL OF NEUROBIOLOGY
JOURNAL OF NEUROSCIENCE
KEIO JOURNAL OF MEDICINE
NEUROBIOLOGY OF AGING
PROCEEDINGS- NATIONAL ACADEMY OF SCIENCES USA
SCIENCE -NEW YORK THEN WASHINGTON-
Thesis (Ph. D.)--Johns Hopkins University, 1976